BRD-K21680192_mitoxantrone_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

484 genes differentially expressed following the BRD-K21680192_mitoxantrone_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ACBD3 acyl-CoA binding domain containing 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCK3 aarF domain containing kinase 3
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMOTL2 angiomotin like 2
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATMIN ATM interactor
BCL10 B-cell CLL/lymphoma 10
BCL6 B-cell CLL/lymphoma 6
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
BLCAP bladder cancer associated protein
BRD2 bromodomain containing 2
BST2 bone marrow stromal cell antigen 2
BTG2 BTG family, member 2
BTG3 BTG family, member 3
C1ORF116 chromosome 1 open reading frame 116
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CCDC90B coiled-coil domain containing 90B
CCDC92 coiled-coil domain containing 92
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL5 chemokine (C-C motif) ligand 5
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES2 carboxylesterase 2
CFB complement factor B
CHIC2 cysteine-rich hydrophobic domain 2
CHMP5 charged multivesicular body protein 5
CHMP6 charged multivesicular body protein 6
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCA2 chloride channel accessory 2
CLEC2B C-type lectin domain family 2, member B
CLGN calmegin
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CPM carboxypeptidase M
CSRNP2 cysteine-serine-rich nuclear protein 2
CST3 cystatin C
CTTN cortactin
CXADR coxsackie virus and adenovirus receptor
CXCL13 chemokine (C-X-C motif) ligand 13
CYB5R1 cytochrome b5 reductase 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DFNA5 deafness, autosomal dominant 5
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
DST dystonin
DUSP14 dual specificity phosphatase 14
DUSP2 dual specificity phosphatase 2
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB2 ephrin-B2
EGR1 early growth response 1
EGR2 early growth response 2
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV5 ets variant 5
EXOSC4 exosome component 4
F13A1 coagulation factor XIII, A1 polypeptide
F8 coagulation factor VIII, procoagulant component
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FOXO4 forkhead box O4
FUCA1 fucosidase, alpha-L- 1, tissue
FZD6 frizzled class receptor 6
G0S2 G0/G1 switch 2
GAA glucosidase, alpha; acid
GADD45A growth arrest and DNA-damage-inducible, alpha
GALE UDP-galactose-4-epimerase
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GLS glutaminase
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
GPER1 G protein-coupled estrogen receptor 1
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
HCP5 HLA complex P5 (non-protein coding)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST3H2A histone cluster 3, H2a
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HOMER3 homer scaffolding protein 3
HOXA5 homeobox A5
IER2 immediate early response 2
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IGHM immunoglobulin heavy constant mu
INPP1 inositol polyphosphate-1-phosphatase
ISG15 ISG15 ubiquitin-like modifier
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KDSR 3-ketodihydrosphingosine reductase
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY75 lymphocyte antigen 75
MAB21L1 mab-21-like 1 (C. elegans)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGED2 melanoma antigen family D2
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MICALL1 MICAL-like 1
MIR22HG MIR22 host gene
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MT2A metallothionein 2A
N4BP2L2 NEDD4 binding protein 2-like 2
NCF2 neutrophil cytosolic factor 2
NINJ1 ninjurin 1
ORAI3 ORAI calcium release-activated calcium modulator 3
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCDH7 protocadherin 7
PDLIM4 PDZ and LIM domain 4
PEG3 paternally expressed 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PI3 peptidase inhibitor 3, skin-derived
PLA2G15 phospholipase A2, group XV
PLAT plasminogen activator, tissue
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PLXNA1 plexin A1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTN pleiotrophin
PTX3 pentraxin 3, long
RALGDS ral guanine nucleotide dissociation stimulator
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBKS ribokinase
REG1A regenerating islet-derived 1 alpha
RPP38 ribonuclease P/MRP 38kDa subunit
RPS27L ribosomal protein S27-like
RRAGD Ras-related GTP binding D
RSL1D1 ribosomal L1 domain containing 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A2 S100 calcium binding protein A2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SCPEP1 serine carboxypeptidase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
SFN stratifin
SFXN3 sideroflexin 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SLFN12 schlafen family member 12
SMG8 SMG8 nonsense mediated mRNA decay factor
SNAI2 snail family zinc finger 2
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOX9 SRY (sex determining region Y)-box 9
SPATA20 spermatogenesis associated 20
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC2 stanniocalcin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBX3 T-box 3
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP1 TIMP metallopeptidase inhibitor 1
TKTL1 transketolase-like 1
TMEM59 transmembrane protein 59
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOB1 transducer of ERBB2, 1
TOR1A torsin family 1, member A (torsin A)
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM22 tripartite motif containing 22
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TUFT1 tuftelin 1
TUSC3 tumor suppressor candidate 3
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
UBL3 ubiquitin-like 3
VAMP8 vesicle-associated membrane protein 8
VAT1 vesicle amine transport 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
ZMAT3 zinc finger, matrin-type 3
ZNF468 zinc finger protein 468
ZNF529 zinc finger protein 529

decreased expression

Symbol Name
AARS alanyl-tRNA synthetase
ADAM10 ADAM metallopeptidase domain 10
AEBP1 AE binding protein 1
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AQP1 aquaporin 1 (Colton blood group)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
AURKA aurora kinase A
AURKB aurora kinase B
AUTS2 autism susceptibility candidate 2
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C4BPA complement component 4 binding protein, alpha
CA2 carbonic anhydrase II
CBS cystathionine-beta-synthase
CBX5 chromobox homolog 5
CCNA2 cyclin A2
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDCA3 cell division cycle associated 3
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPN centromere protein N
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CFH complement factor H
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHEK1 checkpoint kinase 1
CIT citron rho-interacting serine/threonine kinase
CKS1B CDC28 protein kinase regulatory subunit 1B
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
COL9A3 collagen, type IX, alpha 3
CP ceruloplasmin (ferroxidase)
CREB3L2 cAMP responsive element binding protein 3-like 2
CRYM crystallin, mu
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST1 cystatin SN
CUX1 cut-like homeobox 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
DCN decorin
DHFR dihydrofolate reductase
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNM1 dynamin 1
DOCK4 dedicator of cytokinesis 4
DPYSL2 dihydropyrimidinase-like 2
DSCC1 DNA replication and sister chromatid cohesion 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUT deoxyuridine triphosphatase
ECT2 epithelial cell transforming 2
EHBP1 EH domain binding protein 1
EIF5A eukaryotic translation initiation factor 5A
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
ENOSF1 enolase superfamily member 1
EXO1 exonuclease 1
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FANCI Fanconi anemia, complementation group I
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FOXM1 forkhead box M1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDI2 GDP dissociation inhibitor 2
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GMPS guanine monphosphate synthase
GPX2 glutathione peroxidase 2
GRB14 growth factor receptor-bound protein 14
H2AFV H2A histone family, member V
HBB hemoglobin, beta
HBD hemoglobin, delta
HELLS helicase, lymphoid-specific
HILPDA hypoxia inducible lipid droplet-associated
HJURP Holliday junction recognition protein
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IARS isoleucyl-tRNA synthetase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IPO7 importin 7
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF4A kinesin family member 4A
KNTC1 kinetochore associated 1
LAMP5 lysosomal-associated membrane protein family, member 5
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMNB1 lamin B1
LMNB2 lamin B2
LOXL1 lysyl oxidase-like 1
LPL lipoprotein lipase
LYZ lysozyme
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP7 microtubule-associated protein 7
MATN2 matrilin 2
MBNL1 muscleblind-like splicing regulator 1
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MELK maternal embryonic leucine zipper kinase
MGLL monoglyceride lipase
MID1 midline 1
MKI67 marker of proliferation Ki-67
MLPH melanophilin
MSH6 mutS homolog 6
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYO10 myosin X
NAP1L1 nucleosome assembly protein 1-like 1
NCAPG non-SMC condensin I complex, subunit G
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NCOA3 nuclear receptor coactivator 3
NEK2 NIMA-related kinase 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTS neurotensin
NUSAP1 nucleolar and spindle associated protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBK PDZ binding kinase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PDS5A PDS5 cohesin associated factor A
PECR peroxisomal trans-2-enoyl-CoA reductase
PFAS phosphoribosylformylglycinamidine synthase
PFKP phosphofructokinase, platelet
PGD phosphogluconate dehydrogenase
PHGDH phosphoglycerate dehydrogenase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PON3 paraoxonase 3
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRC1 protein regulator of cytokinesis 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSAT1 phosphoserine aminotransferase 1
PSD3 pleckstrin and Sec7 domain containing 3
PYCR1 pyrroline-5-carboxylate reductase 1
RAD54B RAD54 homolog B (S. cerevisiae)
RAP1GAP RAP1 GTPase activating protein
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBPMS RNA binding protein with multiple splicing
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RHOBTB3 Rho-related BTB domain containing 3
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SEPHS1 selenophosphate synthetase 1
SEPT11 septin 11
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC4 structural maintenance of chromosomes 4
SNAP25 synaptosomal-associated protein, 25kDa
SPC25 SPC25, NDC80 kinetochore complex component
SPTBN1 spectrin, beta, non-erythrocytic 1
STAG2 stromal antigen 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STMN1 stathmin 1
STMN2 stathmin 2
SYT1 synaptotagmin I
TACC3 transforming, acidic coiled-coil containing protein 3
TCF12 transcription factor 12
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TIMELESS timeless circadian clock
TK1 thymidine kinase 1, soluble
TM9SF3 transmembrane 9 superfamily member 3
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM97 transmembrane protein 97
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TPR translocated promoter region, nuclear basket protein
TPX2 TPX2, microtubule-associated
TRIP13 thyroid hormone receptor interactor 13
TSPAN13 tetraspanin 13
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VRK1 vaccinia related kinase 1
VRK2 vaccinia related kinase 2
XIST X inactive specific transcript (non-protein coding)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZWINT ZW10 interacting kinetochore protein