BRD-K21672174_Ro 28-1675 ?_DV90_6.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K21672174_Ro 28-1675 ?_DV90_6.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA3 annexin A3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX1 armadillo repeat containing, X-linked 1
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
BTG1 B-cell translocation gene 1, anti-proliferative
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLGN calmegin
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
FAM129A family with sequence similarity 129, member A
FHL2 four and a half LIM domains 2
G0S2 G0/G1 switch 2
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GSAP gamma-secretase activating protein
HCAR3 hydroxycarboxylic acid receptor 3
HLA-B major histocompatibility complex, class I, B
HOXB2 homeobox B2
HOXB6 homeobox B6
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JUN jun proto-oncogene
KIAA1033 KIAA1033
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MEIS2 Meis homeobox 2
MGP matrix Gla protein
MMP1 matrix metallopeptidase 1
NFIL3 nuclear factor, interleukin 3 regulated
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFRL platelet-derived growth factor receptor-like
PEG3 paternally expressed 3
PER1 period circadian clock 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PXDN peroxidasin
QPCT glutaminyl-peptide cyclotransferase
RND3 Rho family GTPase 3
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLK2 tousled-like kinase 2
TPBG trophoblast glycoprotein
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
WSB1 WD repeat and SOCS box containing 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
B3GNT1
CDC25A cell division cycle 25A
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
DEFB1 defensin, beta 1
DUSP7 dual specificity phosphatase 7
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP1 fatty acid binding protein 1, liver
FASTKD5 FAST kinase domains 5
GRB7 growth factor receptor-bound protein 7
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MXRA7 matrix-remodelling associated 7
NAAA N-acylethanolamine acid amidase
NT5DC2 5'-nucleotidase domain containing 2
PGAP3 post-GPI attachment to proteins 3
PI3 peptidase inhibitor 3, skin-derived
PLK1 polo-like kinase 1
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RPA1 replication protein A1, 70kDa
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RUNX3 runt-related transcription factor 3
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STK25 serine/threonine kinase 25
TFRC transferrin receptor
TMEM109 transmembrane protein 109