BRD-K20986251_BL-076_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K20986251_BL-076_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
ANXA5 annexin A5
APOD apolipoprotein D
ASRGL1 asparaginase like 1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
C1ORF115 chromosome 1 open reading frame 115
C6ORF62 chromosome 6 open reading frame 62
CD163 CD163 molecule
CSNK1A1 casein kinase 1, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLG5 discs, large homolog 5 (Drosophila)
EGFR epidermal growth factor receptor
ELOVL5 ELOVL fatty acid elongase 5
FKBP5 FK506 binding protein 5
FOXO3 forkhead box O3
FUCA1 fucosidase, alpha-L- 1, tissue
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
KIAA1324 KIAA1324
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
LGMN legumain
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL7A methyltransferase like 7A
MMP9 matrix metallopeptidase 9
MSX1 msh homeobox 1
MYBPC1 myosin binding protein C, slow type
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
S100A10 S100 calcium binding protein A10
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOX9 SRY (sex determining region Y)-box 9
SPDEF SAM pointed domain containing ETS transcription factor
SYBU syntabulin (syntaxin-interacting)
SYNM synemin, intermediate filament protein
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZBTB16 zinc finger and BTB domain containing 16
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
BCHE butyrylcholinesterase
CA12 carbonic anhydrase XII
CCDC85B coiled-coil domain containing 85B
CCND2 cyclin D2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DEFB1 defensin, beta 1
EPHA3 EPH receptor A3
GRWD1 glutamate-rich WD repeat containing 1
GUSBP11 glucuronidase, beta pseudogene 11
HOPX HOP homeobox
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS4 lectin, galactoside-binding, soluble, 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
NREP neuronal regeneration related protein
PDGFC platelet derived growth factor C
PEG3 paternally expressed 3
RBP1 retinol binding protein 1, cellular
RGS5 regulator of G-protein signaling 5
SCG5 secretogranin V
SST somatostatin
TCF21 transcription factor 21
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TSPAN8 tetraspanin 8
TYRP1 tyrosinase-related protein 1
WT1 Wilms tumor 1