BRD-K20755323_-666_SW948_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K20755323_-666_SW948_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADM adrenomedullin
ARL4C ADP-ribosylation factor-like 4C
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALR calreticulin
CCND2 cyclin D2
CD9 CD9 molecule
CDK14 cyclin-dependent kinase 14
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
CLC Charcot-Leyden crystal galectin
CLIC4 chloride intracellular channel 4
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
FBN2 fibrillin 2
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
H1F0 H1 histone family, member 0
H2AFV H2A histone family, member V
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXC10 homeobox C10
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HYOU1 hypoxia up-regulated 1
IFRD1 interferon-related developmental regulator 1
IGFBP5 insulin-like growth factor binding protein 5
ITM2C integral membrane protein 2C
KRT15 keratin 15, type I
LINC00341 long intergenic non-protein coding RNA 341
NBPF10 neuroblastoma breakpoint family, member 10
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PALLD palladin, cytoskeletal associated protein
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHGDH phosphoglycerate dehydrogenase
POSTN periostin, osteoblast specific factor
PPAP2B phosphatidic acid phosphatase type 2B
RCAN2 regulator of calcineurin 2
RNASE4 ribonuclease, RNase A family, 4
S100A14 S100 calcium binding protein A14
S100A9 S100 calcium binding protein A9
SEC63 SEC63 homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SULF1 sulfatase 1
THY1 Thy-1 cell surface antigen
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TNNT1 troponin T type 1 (skeletal, slow)
TPBG trophoblast glycoprotein
TSC22D3 TSC22 domain family, member 3
TXNRD1 thioredoxin reductase 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UGP2 UDP-glucose pyrophosphorylase 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD47 CD47 molecule
CLU clusterin
CTSH cathepsin H
CXCL2 chemokine (C-X-C motif) ligand 2
DHCR7 7-dehydrocholesterol reductase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GLS glutaminase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
IFI27 interferon, alpha-inducible protein 27
IL13RA2 interleukin 13 receptor, alpha 2
LAMP1 lysosomal-associated membrane protein 1
LAPTM4B lysosomal protein transmembrane 4 beta
LOC100505650 uncharacterized LOC100505650
MCOLN1 mucolipin 1
MRPS30 mitochondrial ribosomal protein S30
MX2 MX dynamin-like GTPase 2
PLA1A phospholipase A1 member A
RBP1 retinol binding protein 1, cellular
RPL36 ribosomal protein L36
RPL37A ribosomal protein L37a
SFTPB surfactant protein B
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SQLE squalene epoxidase
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
ZNF217 zinc finger protein 217
ZW10 zw10 kinetochore protein