BRD-K20755323_-666_HT29_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K20755323_-666_HT29_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAST calpastatin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDK14 cyclin-dependent kinase 14
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CLEC2B C-type lectin domain family 2, member B
CLIC5 chloride intracellular channel 5
CNN3 calponin 3, acidic
COLEC12 collectin sub-family member 12
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRELD2 cysteine-rich with EGF-like domains 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DENND1B DENN/MADD domain containing 1B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPAS1 endothelial PAS domain protein 1
FGG fibrinogen gamma chain
FN1 fibronectin 1
FOXF2 forkhead box F2
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
GRB7 growth factor receptor-bound protein 7
GSTA1 glutathione S-transferase alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR6 lysophosphatidic acid receptor 6
MICALL1 MICAL-like 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NUCB2 nucleobindin 2
NVL nuclear VCP-like
OSBPL10 oxysterol binding protein-like 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTPRO protein tyrosine phosphatase, receptor type, O
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB1D2 secretoglobin, family 1D, member 2
SDC4 syndecan 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
TESK1 testis-specific kinase 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM13 tripartite motif containing 13
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
CCNG1 cyclin G1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENOSF1 enolase superfamily member 1
EPCAM epithelial cell adhesion molecule
FAM171A1 family with sequence similarity 171, member A1
FAM46A family with sequence similarity 46, member A
FAR2 fatty acyl CoA reductase 2
GCA grancalcin, EF-hand calcium binding protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
MRPS30 mitochondrial ribosomal protein S30
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROM1 prominin 1
RAD23B RAD23 homolog B (S. cerevisiae)
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SESN1 sestrin 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)