BRD-K20526256_HG-14-10-04_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

129 genes differentially expressed following the BRD-K20526256_HG-14-10-04_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ASPN asporin
ATF4 activating transcription factor 4
ATMIN ATM interactor
ATP9A ATPase, class II, type 9A
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C1ORF115 chromosome 1 open reading frame 115
C1R complement component 1, r subcomponent
C8ORF4 chromosome 8 open reading frame 4
CBS cystathionine-beta-synthase
CDK14 cyclin-dependent kinase 14
CFB complement factor B
CLDN10 claudin 10
COBL cordon-bleu WH2 repeat protein
COL11A1 collagen, type XI, alpha 1
COLEC12 collectin sub-family member 12
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDIT4 DNA-damage-inducible transcript 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNA1 ephrin-A1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPHA3 EPH receptor A3
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
GREM1 gremlin 1, DAN family BMP antagonist
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
KIAA0485 uncharacterized LOC57235
MDFIC MyoD family inhibitor domain containing
METTL7A methyltransferase like 7A
MPST mercaptopyruvate sulfurtransferase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTUS1 microtubule associated tumor suppressor 1
MYH10 myosin, heavy chain 10, non-muscle
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDZK1IP1 PDZK1 interacting protein 1
PHGDH phosphoglycerate dehydrogenase
PIEZO2 piezo-type mechanosensitive ion channel component 2
PROM1 prominin 1
PTCH1 patched 1
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOX11 SRY (sex determining region Y)-box 11
SPON1 spondin 1, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULF1 sulfatase 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TGM2 transglutaminase 2
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS1 tensin 1
TWF2 twinfilin actin binding protein 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VDAC1 voltage-dependent anion channel 1
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ALDOA aldolase A, fructose-bisphosphate
ANGPT1 angiopoietin 1
ANXA1 annexin A1
AREG amphiregulin
AURKA aurora kinase A
AZU1 azurocidin 1
BIRC5 baculoviral IAP repeat containing 5
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CCNA2 cyclin A2
CD24 CD24 molecule
CDC20 cell division cycle 20
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CKS2 CDC28 protein kinase regulatory subunit 2
CLC Charcot-Leyden crystal galectin
CLU clusterin
COL1A2 collagen, type I, alpha 2
COL4A6 collagen, type IV, alpha 6
COL6A3 collagen, type VI, alpha 3
CORO1A coronin, actin binding protein, 1A
CPA3 carboxypeptidase A3 (mast cell)
CST7 cystatin F (leukocystatin)
CSTA cystatin A (stefin A)
CX3CR1 chemokine (C-X3-C motif) receptor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELANE elastase, neutrophil expressed
EREG epiregulin
EXOSC4 exosome component 4
FAM46A family with sequence similarity 46, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEN1 flap structure-specific endonuclease 1
FOSL1 FOS-like antigen 1
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LGALS3 lectin, galactoside-binding, soluble, 3
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGED1 melanoma antigen family D1
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
MPO myeloperoxidase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP1 plakophilin 1
PLK1 polo-like kinase 1
PRTN3 proteinase 3
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SLN sarcolipin
SMC4 structural maintenance of chromosomes 4
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIP13 thyroid hormone receptor interactor 13
TUBA4A tubulin, alpha 4a
TUBB3 tubulin, beta 3 class III
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZWINT ZW10 interacting kinetochore protein