BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
CA12 carbonic anhydrase XII
COL3A1 collagen, type III, alpha 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HOPX HOP homeobox
IL32 interleukin 32
KRT7 keratin 7, type II
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SORBS2 sorbin and SH3 domain containing 2
SOX9 SRY (sex determining region Y)-box 9
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGM2 transglutaminase 2
WSB2 WD repeat and SOCS box containing 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BTG3 BTG family, member 3
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CDC42 cell division cycle 42
CLCA1 chloride channel accessory 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
EIF5A eukaryotic translation initiation factor 5A
GPM6B glycoprotein M6B
GREM1 gremlin 1, DAN family BMP antagonist
IFI6 interferon, alpha-inducible protein 6
IL1R1 interleukin 1 receptor, type I
ISG15 ISG15 ubiquitin-like modifier
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
L1CAM L1 cell adhesion molecule
LTBP1 latent transforming growth factor beta binding protein 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MECOM MDS1 and EVI1 complex locus
MIR22HG MIR22 host gene
MX1 MX dynamin-like GTPase 1
OLFM4 olfactomedin 4
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PELI1 pellino E3 ubiquitin protein ligase 1
PLN phospholamban
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRO protein tyrosine phosphatase, receptor type, O
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SGCE sarcoglycan, epsilon
SPINK1 serine peptidase inhibitor, Kazal type 1
SST somatostatin
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TRIM2 tripartite motif containing 2
ZNF721 zinc finger protein 721