BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

106 genes differentially expressed following the BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1ORF56 chromosome 1 open reading frame 56
CA2 carbonic anhydrase II
CD44 CD44 molecule (Indian blood group)
COG7 component of oligomeric golgi complex 7
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
DDR1 discoidin domain receptor tyrosine kinase 1
DST dystonin
EXT1 exostosin glycosyltransferase 1
FAM198B family with sequence similarity 198, member B
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GATA3 GATA binding protein 3
GNAS GNAS complex locus
H2AFV H2A histone family, member V
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFNAR1 interferon (alpha, beta and omega) receptor 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MMP10 matrix metallopeptidase 10
MPZL2 myelin protein zero-like 2
NEB nebulin
NPIPB3 nuclear pore complex interacting protein family, member B3
NRCAM neuronal cell adhesion molecule
NXN nucleoredoxin
PBX3 pre-B-cell leukemia homeobox 3
PEG10 paternally expressed 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMM2 phosphomannomutase 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXN paxillin
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SHB Src homology 2 domain containing adaptor protein B
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAP2 signal transducing adaptor family member 2
STX1A syntaxin 1A (brain)
TCTA T-cell leukemia translocation altered
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
WARS tryptophanyl-tRNA synthetase
WDR7 WD repeat domain 7
WT1 Wilms tumor 1
ZFPM2 zinc finger protein, FOG family member 2
ZNF274 zinc finger protein 274
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BAG2 BCL2-associated athanogene 2
CBR3 carbonyl reductase 3
CD59 CD59 molecule, complement regulatory protein
CFD complement factor D (adipsin)
CLU clusterin
COCH cochlin
COMP cartilage oligomeric matrix protein
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DDAH1 dimethylarginine dimethylaminohydrolase 1
DYNLRB1 dynein, light chain, roadblock-type 1
FBXL12 F-box and leucine-rich repeat protein 12
FERMT2 fermitin family member 2
GMDS GDP-mannose 4,6-dehydratase
H1F0 H1 histone family, member 0
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC6 homeobox C6
ICA1 islet cell autoantigen 1, 69kDa
IGFBP1 insulin-like growth factor binding protein 1
IL1R1 interleukin 1 receptor, type I
LXN latexin
MCUR1 mitochondrial calcium uniporter regulator 1
MT1M metallothionein 1M
MT1X metallothionein 1X
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY neuropeptide Y
PDLIM4 PDZ and LIM domain 4
PLTP phospholipid transfer protein
PRSS3 protease, serine, 3
PSD3 pleckstrin and Sec7 domain containing 3
PTGES prostaglandin E synthase
QDPR quinoid dihydropteridine reductase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RPA3 replication protein A3, 14kDa
SACS sacsin molecular chaperone
SFN stratifin
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPSB2 tryptase beta 2 (gene/pseudogene)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1