BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANKRD10 ankyrin repeat domain 10
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CDK19 cyclin-dependent kinase 19
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
ELAVL1 ELAV like RNA binding protein 1
FBN2 fibrillin 2
FCGBP Fc fragment of IgG binding protein
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
IGFBP5 insulin-like growth factor binding protein 5
INSR insulin receptor
LAMA4 laminin, alpha 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MMP3 matrix metallopeptidase 3
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NQO1 NAD(P)H dehydrogenase, quinone 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUNX3 runt-related transcription factor 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFRP1 secreted frizzled-related protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLN sarcolipin
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TTN titin
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALDOB aldolase B, fructose-bisphosphate
ANXA3 annexin A3
ATF3 activating transcription factor 3
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
CAV2 caveolin 2
CLDN10 claudin 10
CST6 cystatin E/M
DEFB1 defensin, beta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
ERVMER34-1 endogenous retrovirus group MER34, member 1
G0S2 G0/G1 switch 2
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPX3 glutathione peroxidase 3
GTF3A general transcription factor IIIA
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H4C histone cluster 1, H4c
IFI27 interferon, alpha-inducible protein 27
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KIAA1033 KIAA1033
KNG1 kininogen 1
LAMC2 laminin, gamma 2
LYRM1 LYR motif containing 1
MMD monocyte to macrophage differentiation-associated
NRIP1 nuclear receptor interacting protein 1
PDZD2 PDZ domain containing 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RASL11B RAS-like, family 11, member B
RBP4 retinol binding protein 4, plasma
RGS2 regulator of G-protein signaling 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SRP72 signal recognition particle 72kDa
TSC22D2 TSC22 domain family, member 2