BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

121 genes differentially expressed following the BRD-K20152659_DIHOMO-GAMMA-LINOLENIC ACID_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1ORF116 chromosome 1 open reading frame 116
C1QA complement component 1, q subcomponent, A chain
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CD27 CD27 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CLDN4 claudin 4
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPP4 dipeptidyl-peptidase 4
DSC3 desmocollin 3
DST dystonin
DUOX1 dual oxidase 1
EXT1 exostosin glycosyltransferase 1
FAM69A family with sequence similarity 69, member A
FBXL12 F-box and leucine-rich repeat protein 12
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
H2AFV H2A histone family, member V
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
INSM1 insulinoma-associated 1
KCNK3 potassium channel, two pore domain subfamily K, member 3
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KRT6B keratin 6B, type II
LAMP3 lysosomal-associated membrane protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAGEA3 melanoma antigen family A3
MALL mal, T-cell differentiation protein-like
MEST mesoderm specific transcript
MET MET proto-oncogene, receptor tyrosine kinase
MSMB microseminoprotein, beta-
NVL nuclear VCP-like
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEK2 pleckstrin 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RFTN1 raftlin, lipid raft linker 1
RSL1D1 ribosomal L1 domain containing 1
SDC1 syndecan 1
SFTPD surfactant protein D
SHB Src homology 2 domain containing adaptor protein B
TACSTD2 tumor-associated calcium signal transducer 2
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TMPRSS2 transmembrane protease, serine 2
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TUSC3 tumor suppressor candidate 3
VEGFA vascular endothelial growth factor A
ZEB1 zinc finger E-box binding homeobox 1
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C14ORF2 chromosome 14 open reading frame 2
CAST calpastatin
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLU clusterin
COMP cartilage oligomeric matrix protein
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
CRIP2 cysteine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYNLRB1 dynein, light chain, roadblock-type 1
EFHD1 EF-hand domain family, member D1
EGR3 early growth response 3
ETNPPL ethanolamine-phosphate phospho-lyase
GAS1 growth arrest-specific 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLDC glycine dehydrogenase (decarboxylating)
GOLT1B golgi transport 1B
GPM6B glycoprotein M6B
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTM3 glutathione S-transferase mu 3 (brain)
IL6ST interleukin 6 signal transducer
LTBP1 latent transforming growth factor beta binding protein 1
LYPD1 LY6/PLAUR domain containing 1
LYPLA1 lysophospholipase I
LYRM1 LYR motif containing 1
MRPS30 mitochondrial ribosomal protein S30
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTS neurotensin
OSBPL1A oxysterol binding protein-like 1A
PBLD phenazine biosynthesis-like protein domain containing
PGAM1 phosphoglycerate mutase 1 (brain)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPIC peptidylprolyl isomerase C (cyclophilin C)
PTX3 pentraxin 3, long
RAB4A RAB4A, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
SCAND1 SCAN domain containing 1
SCRG1 stimulator of chondrogenesis 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRI sorcin
SRSF7 serine/arginine-rich splicing factor 7
STOM stomatin
TFF3 trefoil factor 3 (intestinal)
TPBG trophoblast glycoprotein
TRAK2 trafficking protein, kinesin binding 2
TXNDC9 thioredoxin domain containing 9
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1