BRD-K19220233_JNK-9L_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

103 genes differentially expressed following the BRD-K19220233_JNK-9L_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
IFI6 interferon, alpha-inducible protein 6
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
LAGE3 L antigen family, member 3
MEIS1 Meis homeobox 1
MSN moesin
NPDC1 neural proliferation, differentiation and control, 1
NT5DC2 5'-nucleotidase domain containing 2
OAT ornithine aminotransferase
PSENEN presenilin enhancer gamma secretase subunit
PSPH phosphoserine phosphatase
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TMEM47 transmembrane protein 47
TPGS2 tubulin polyglutamylase complex subunit 2
TSPAN4 tetraspanin 4
WIF1 WNT inhibitory factor 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
BAMBI BMP and activin membrane-bound inhibitor
BTG2 BTG family, member 2
C6ORF62 chromosome 6 open reading frame 62
CANT1 calcium activated nucleotidase 1
CD24 CD24 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLP1 cleavage and polyadenylation factor I subunit 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FASTKD5 FAST kinase domains 5
FILIP1L filamin A interacting protein 1-like
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GPM6B glycoprotein M6B
GTF2B general transcription factor IIB
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HSPA8 heat shock 70kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER5 immediate early response 5
INHBB inhibin, beta B
JADE2 jade family PHD finger 2
KLF5 Kruppel-like factor 5 (intestinal)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT14 keratin 14, type I
KRT19 keratin 19, type I
LCN2 lipocalin 2
LTF lactotransferrin
MAPK6 mitogen-activated protein kinase 6
MAT2A methionine adenosyltransferase II, alpha
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NUP62 nucleoporin 62kDa
NXT1 nuclear transport factor 2-like export factor 1
PLIN2 perilipin 2
PLK2 polo-like kinase 2
PPIF peptidylprolyl isomerase F
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
RAP2B RAP2B, member of RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM15 RNA binding motif protein 15
RET ret proto-oncogene
RNF139 ring finger protein 139
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
SOX4 SRY (sex determining region Y)-box 4
SPATA2 spermatogenesis associated 2
TBPL1 TBP-like 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TXNIP thioredoxin interacting protein
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2S ubiquitin-conjugating enzyme E2S
USP1 ubiquitin specific peptidase 1