BRD-K19220233_JNK-9L_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K19220233_JNK-9L_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ADGRG6 adhesion G protein-coupled receptor G6
BPHL biphenyl hydrolase-like (serine hydrolase)
BST2 bone marrow stromal cell antigen 2
CD47 CD47 molecule
CFB complement factor B
CHL1 cell adhesion molecule L1-like
COL3A1 collagen, type III, alpha 1
CTSA cathepsin A
CTSB cathepsin B
FLNA filamin A, alpha
HOXA5 homeobox A5
HOXC6 homeobox C6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFITM1 interferon induced transmembrane protein 1
KLK3 kallikrein-related peptidase 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LTB lymphotoxin beta (TNF superfamily, member 3)
MEIS1 Meis homeobox 1
PRAME preferentially expressed antigen in melanoma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SKAP2 src kinase associated phosphoprotein 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMC1A structural maintenance of chromosomes 1A
SPON1 spondin 1, extracellular matrix protein
SRPX sushi-repeat containing protein, X-linked
TIMP3 TIMP metallopeptidase inhibitor 3
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ARID4B AT rich interactive domain 4B (RBP1-like)
AUTS2 autism susceptibility candidate 2
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CCL19 chemokine (C-C motif) ligand 19
CD24 CD24 molecule
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CLU clusterin
CXCL12 chemokine (C-X-C motif) ligand 12
DBF4 DBF4 zinc finger
DCLK1 doublecortin-like kinase 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM60A family with sequence similarity 60, member A
GATA3 GATA binding protein 3
HES1 hes family bHLH transcription factor 1
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
IGHM immunoglobulin heavy constant mu
IL1R2 interleukin 1 receptor, type II
INHBB inhibin, beta B
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KIF14 kinesin family member 14
KRT14 keratin 14, type I
KRT19 keratin 19, type I
MAK16 MAK16 homolog (S. cerevisiae)
MAPK6 mitogen-activated protein kinase 6
MAT2A methionine adenosyltransferase II, alpha
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NPY1R neuropeptide Y receptor Y1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP62 nucleoporin 62kDa
PER2 period circadian clock 2
PLK2 polo-like kinase 2
PTGES prostaglandin E synthase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RBPMS RNA binding protein with multiple splicing
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSBN1 round spermatid basic protein 1
S100A2 S100 calcium binding protein A2
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMAD7 SMAD family member 7
SMYD2 SET and MYND domain containing 2
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
STK17A serine/threonine kinase 17a
TBPL1 TBP-like 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
WEE1 WEE1 G2 checkpoint kinase
ZBTB18 zinc finger and BTB domain containing 18
ZHX2 zinc fingers and homeoboxes 2
ZNF217 zinc finger protein 217