BRD-K19220233_JNK-9L_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

217 genes differentially expressed following the BRD-K19220233_JNK-9L_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA9 annexin A9
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BHMT2 betaine--homocysteine S-methyltransferase 2
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
CALB1 calbindin 1, 28kDa
CCL20 chemokine (C-C motif) ligand 20
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CECR1 cat eye syndrome chromosome region, candidate 1
CELF2 CUGBP, Elav-like family member 2
CHERP calcium homeostasis endoplasmic reticulum protein
COL4A5 collagen, type IV, alpha 5
COL6A1 collagen, type VI, alpha 1
COTL1 coactosin-like F-actin binding protein 1
CRYAB crystallin, alpha B
CRYL1 crystallin, lambda 1
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DMD dystrophin
EGR1 early growth response 1
EGR3 early growth response 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FAM46A family with sequence similarity 46, member A
FAM63A family with sequence similarity 63, member A
FAM8A1 family with sequence similarity 8, member A1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPM6B glycoprotein M6B
GPX3 glutathione peroxidase 3
GRB14 growth factor receptor-bound protein 14
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HLA-E major histocompatibility complex, class I, E
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL17RB interleukin 17 receptor B
IL2RG interleukin 2 receptor, gamma
ITGAV integrin, alpha V
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
LMO4 LIM domain only 4
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MEF2C myocyte enhancer factor 2C
METRN meteorin, glial cell differentiation regulator
MICB MHC class I polypeptide-related sequence B
MIR22HG MIR22 host gene
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MXI1 MAX interactor 1, dimerization protein
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NME4 NME/NM23 nucleoside diphosphate kinase 4
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRN1 neuritin 1
OLFM1 olfactomedin 1
PAH phenylalanine hydroxylase
PAM peptidylglycine alpha-amidating monooxygenase
PDZK1 PDZ domain containing 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG3 paternally expressed 3
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RAP2C RAP2C, member of RAS oncogene family
RBP1 retinol binding protein 1, cellular
RBP4 retinol binding protein 4, plasma
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
SRPR signal recognition particle receptor (docking protein)
STC2 stanniocalcin 2
STK10 serine/threonine kinase 10
STK26 serine/threonine protein kinase 26
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPP1 tripeptidyl peptidase I
TRBC1 T cell receptor beta constant 1
TSPAN1 tetraspanin 1
TSPAN7 tetraspanin 7
TTC3 tetratricopeptide repeat domain 3
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZIC1 Zic family member 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADGRG2 adhesion G protein-coupled receptor G2
AHNAK AHNAK nucleoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BLMH bleomycin hydrolase
C10ORF10 chromosome 10 open reading frame 10
C2CD5 C2 calcium-dependent domain containing 5
C3ORF14 chromosome 3 open reading frame 14
CASC3 cancer susceptibility candidate 3
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHGB chromogranin B
CKS1B CDC28 protein kinase regulatory subunit 1B
CLU clusterin
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL10A1 collagen, type X, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCK deoxycytidine kinase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
DPYSL3 dihydropyrimidinase-like 3
ECD ecdysoneless homolog (Drosophila)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELOVL1 ELOVL fatty acid elongase 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FA2H fatty acid 2-hydroxylase
FAM111A family with sequence similarity 111, member A
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GALE UDP-galactose-4-epimerase
GAS1 growth arrest-specific 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPX2 glutathione peroxidase 2
H2AFX H2A histone family, member X
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1L hematological and neurological expressed 1-like
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IL1R2 interleukin 1 receptor, type II
INHBA inhibin, beta A
INHBB inhibin, beta B
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KIAA1033 KIAA1033
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT18 keratin 18, type I
KRT4 keratin 4, type II
KRT7 keratin 7, type II
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MED24 mediator complex subunit 24
MELK maternal embryonic leucine zipper kinase
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MSL1 male-specific lethal 1 homolog (Drosophila)
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NET1 neuroepithelial cell transforming 1
NOP56 NOP56 ribonucleoprotein
NTS neurotensin
OPN3 opsin 3
PCNA proliferating cell nuclear antigen
PLCB4 phospholipase C, beta 4
PRKCD protein kinase C, delta
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFC4 replication factor C (activator 1) 4, 37kDa
RIN2 Ras and Rab interactor 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RRM2 ribonucleotide reductase M2
RUFY3 RUN and FYVE domain containing 3
S100A11 S100 calcium binding protein A11
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLPI secretory leukocyte peptidase inhibitor
SMC4 structural maintenance of chromosomes 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SOCS1 suppressor of cytokine signaling 1
SPRR3 small proline-rich protein 3
SRSF6 serine/arginine-rich splicing factor 6
ST7 suppression of tumorigenicity 7
STIP1 stress-induced phosphoprotein 1
TAGLN2 transgelin 2
TBC1D4 TBC1 domain family, member 4
TFRC transferrin receptor
TMEM97 transmembrane protein 97
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRIM29 tripartite motif containing 29
TWF2 twinfilin actin binding protein 2
TYMS thymidylate synthetase
UBE3C ubiquitin protein ligase E3C
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
YBX3 Y box binding protein 3
ZDHHC13 zinc finger, DHHC-type containing 13
ZWINT ZW10 interacting kinetochore protein