BRD-K19220233_JNK-9L_PC3_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K19220233_JNK-9L_PC3_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK3 aarF domain containing kinase 3
ADM adrenomedullin
BEX4 brain expressed, X-linked 4
CCDC92 coiled-coil domain containing 92
CCL20 chemokine (C-C motif) ligand 20
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CERK ceramide kinase
CRIP1 cysteine-rich protein 1 (intestinal)
CTSZ cathepsin Z
DALRD3 DALR anticodon binding domain containing 3
DSP desmoplakin
EPCAM epithelial cell adhesion molecule
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FRZB frizzled-related protein
KRT19 keratin 19, type I
MYO5C myosin VC
NELL2 NEL-like 2 (chicken)
OBSL1 obscurin-like 1
OXA1L oxidase (cytochrome c) assembly 1-like
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PODXL podocalyxin-like
RBP4 retinol binding protein 4, plasma
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SMAD7 SMAD family member 7
SPAG4 sperm associated antigen 4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SQLE squalene epoxidase
TFF1 trefoil factor 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAPPC6A trafficking protein particle complex 6A
UBE3B ubiquitin protein ligase E3B

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ATF5 activating transcription factor 5
BCHE butyrylcholinesterase
CD200 CD200 molecule
CDA cytidine deaminase
COL3A1 collagen, type III, alpha 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETV1 ets variant 1
FAM129A family with sequence similarity 129, member A
HAL histidine ammonia-lyase
HOXB6 homeobox B6
HOXB7 homeobox B7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IGSF3 immunoglobulin superfamily, member 3
INHBB inhibin, beta B
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LRRC17 leucine rich repeat containing 17
MEGF9 multiple EGF-like-domains 9
MEIS2 Meis homeobox 2
MGLL monoglyceride lipase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NT5E 5'-nucleotidase, ecto (CD73)
PLAT plasminogen activator, tissue
PRSS23 protease, serine, 23
PTN pleiotrophin
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RND3 Rho family GTPase 3
SNAP25 synaptosomal-associated protein, 25kDa
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TBL1X transducin (beta)-like 1X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLE4 transducin-like enhancer of split 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VCAN versican
VSIG4 V-set and immunoglobulin domain containing 4
WNT5A wingless-type MMTV integration site family, member 5A
ZCCHC24 zinc finger, CCHC domain containing 24