BRD-K19220233_JNK-9L_MDAMB231_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the BRD-K19220233_JNK-9L_MDAMB231_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANXA1 annexin A1
APLP2 amyloid beta (A4) precursor-like protein 2
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BACE2 beta-site APP-cleaving enzyme 2
BTG2 BTG family, member 2
C1QA complement component 1, q subcomponent, A chain
CADM1 cell adhesion molecule 1
CCL20 chemokine (C-C motif) ligand 20
CD3D CD3d molecule, delta (CD3-TCR complex)
CD84 CD84 molecule
CETN2 centrin, EF-hand protein, 2
CFD complement factor D (adipsin)
CIB1 calcium and integrin binding 1 (calmyrin)
CKB creatine kinase, brain
COL11A1 collagen, type XI, alpha 1
COL6A1 collagen, type VI, alpha 1
CPE carboxypeptidase E
CTTN cortactin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DSP desmoplakin
EGFL6 EGF-like-domain, multiple 6
ERBB4 erb-b2 receptor tyrosine kinase 4
ESD esterase D
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUK1 guanylate kinase 1
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1C histone cluster 1, H1c
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGN5 high mobility group nucleosome binding domain 5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IL1R1 interleukin 1 receptor, type I
IL7R interleukin 7 receptor
ITM2A integral membrane protein 2A
LAMP2 lysosomal-associated membrane protein 2
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LGMN legumain
LPPR4 lipid phosphate phosphatase-related protein type 4
MAOA monoamine oxidase A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP1 matrix metallopeptidase 1
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUCB1 nucleobindin 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PERP PERP, TP53 apoptosis effector
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRDX4 peroxiredoxin 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROS1 protein S (alpha)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRC protein tyrosine phosphatase, receptor type, C
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP1 retinol binding protein 1, cellular
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFTPC surfactant protein C
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SNX10 sorting nexin 10
SORD sorbitol dehydrogenase
SPARCL1 SPARC-like 1 (hevin)
SPON2 spondin 2, extracellular matrix protein
SSR4 signal sequence receptor, delta
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFPI2 tissue factor pathway inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM14B transmembrane protein 14B
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPGS2 tubulin polyglutamylase complex subunit 2
TSPAN4 tetraspanin 4
TSPAN7 tetraspanin 7
TTC3 tetratricopeptide repeat domain 3
TUSC3 tumor suppressor candidate 3
TYROBP TYRO protein tyrosine kinase binding protein
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
VWF von Willebrand factor
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ARF6 ADP-ribosylation factor 6
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BLMH bleomycin hydrolase
CALML5 calmodulin-like 5
CCNA2 cyclin A2
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDK7 cyclin-dependent kinase 7
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPA centromere protein A
CEP55 centrosomal protein 55kDa
CLTA clathrin, light chain A
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTBP2 C-terminal binding protein 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNMBP dynamin binding protein
EED embryonic ectoderm development
FBL fibrillarin
FEN1 flap structure-specific endonuclease 1
FZD7 frizzled class receptor 7
GCH1 GTP cyclohydrolase 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
ILF3 interleukin enhancer binding factor 3, 90kDa
JADE2 jade family PHD finger 2
KEAP1 kelch-like ECH-associated protein 1
KRT7 keratin 7, type II
LASP1 LIM and SH3 protein 1
LBR lamin B receptor
LIPG lipase, endothelial
LMNB1 lamin B1
LTF lactotransferrin
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM3 minichromosome maintenance complex component 3
MCM7 minichromosome maintenance complex component 7
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
MSH6 mutS homolog 6
MYO10 myosin X
NASP nuclear autoantigenic sperm protein (histone-binding)
NET1 neuroepithelial cell transforming 1
NOP56 NOP56 ribonucleoprotein
PCGF2 polycomb group ring finger 2
PCNA proliferating cell nuclear antigen
PDHX pyruvate dehydrogenase complex, component X
PDS5A PDS5 cohesin associated factor A
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLK2 polo-like kinase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POSTN periostin, osteoblast specific factor
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
RAD23B RAD23 homolog B (S. cerevisiae)
RAE1 ribonucleic acid export 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RIN2 Ras and Rab interactor 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SRSF5 serine/arginine-rich splicing factor 5
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TBP TATA box binding protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLR4 toll-like receptor 4
TMPO thymopoietin
TMX4 thioredoxin-related transmembrane protein 4
TRAM2 translocation associated membrane protein 2
TRAPPC3 trafficking protein particle complex 3
TSPYL5 TSPY-like 5
TUBA4A tubulin, alpha 4a
TXLNA taxilin alpha
USP1 ubiquitin specific peptidase 1
USP22 ubiquitin specific peptidase 22
VCAN versican
WSB1 WD repeat and SOCS box containing 1
XPO1 exportin 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon