BRD-K19220233_JNK-9L_MDAMB231_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

137 genes differentially expressed following the BRD-K19220233_JNK-9L_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADAT1 adenosine deaminase, tRNA-specific 1
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
BRD4 bromodomain containing 4
CD52 CD52 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CES2 carboxylesterase 2
CHERP calcium homeostasis endoplasmic reticulum protein
CLDN10 claudin 10
CREB1 cAMP responsive element binding protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GNPDA1 glucosamine-6-phosphate deaminase 1
GTF2B general transcription factor IIB
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H3H histone cluster 1, H3h
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HOPX HOP homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
IER5 immediate early response 5
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL6R interleukin 6 receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MCTP1 multiple C2 domains, transmembrane 1
MIEF1 mitochondrial elongation factor 1
MSMB microseminoprotein, beta-
MXRA5 matrix-remodelling associated 5
NMU neuromedin U
NQO1 NAD(P)H dehydrogenase, quinone 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PELI1 pellino E3 ubiquitin protein ligase 1
PIR pirin (iron-binding nuclear protein)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIF peptidylprolyl isomerase F
RGCC regulator of cell cycle
RIT1 Ras-like without CAAX 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNN stannin
SQSTM1 sequestosome 1
STAB1 stabilin 1
TBX3 T-box 3
TUBB2A tubulin, beta 2A class IIa
VWF von Willebrand factor
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
ZBED4 zinc finger, BED-type containing 4

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
APOD apolipoprotein D
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATF1 activating transcription factor 1
BBX bobby sox homolog (Drosophila)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C16ORF45 chromosome 16 open reading frame 45
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASC3 cancer susceptibility candidate 3
CAST calpastatin
CCND2 cyclin D2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DPYSL2 dihydropyrimidinase-like 2
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ETV1 ets variant 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALE UDP-galactose-4-epimerase
GLRX glutaredoxin (thioltransferase)
GMDS GDP-mannose 4,6-dehydratase
GSTA4 glutathione S-transferase alpha 4
GYG1 glycogenin 1
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HOXB7 homeobox B7
HOXC6 homeobox C6
IARS isoleucyl-tRNA synthetase
INA internexin neuronal intermediate filament protein, alpha
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INTS3 integrator complex subunit 3
ITGA6 integrin, alpha 6
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF20A kinesin family member 20A
LTF lactotransferrin
MCM3 minichromosome maintenance complex component 3
MMP9 matrix metallopeptidase 9
MUT methylmalonyl CoA mutase
MX1 MX dynamin-like GTPase 1
MYO6 myosin VI
NEK7 NIMA-related kinase 7
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCNA proliferating cell nuclear antigen
PDLIM5 PDZ and LIM domain 5
PLBD1 phospholipase B domain containing 1
PLCB4 phospholipase C, beta 4
PPA2 pyrophosphatase (inorganic) 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PWP1 PWP1 homolog (S. cerevisiae)
RBBP4 retinoblastoma binding protein 4
RCAN1 regulator of calcineurin 1
REXO2 RNA exonuclease 2
RHOBTB3 Rho-related BTB domain containing 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STC1 stanniocalcin 1
STOM stomatin
SYT1 synaptotagmin I
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM50A transmembrane protein 50A
TRIM22 tripartite motif containing 22
TSPYL5 TSPY-like 5
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
ZBTB38 zinc finger and BTB domain containing 38
ZIC1 Zic family member 1