BRD-K19220233_JNK-9L_MDAMB231_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

95 genes differentially expressed following the BRD-K19220233_JNK-9L_MDAMB231_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD6 abhydrolase domain containing 6
AKR1C1 aldo-keto reductase family 1, member C1
ANKRD10 ankyrin repeat domain 10
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES2 carboxylesterase 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5R1 cytochrome b5 reductase 1
DHCR24 24-dehydrocholesterol reductase
ETFB electron-transfer-flavoprotein, beta polypeptide
GLS glutaminase
H2BFS H2B histone family, member S (pseudogene)
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
L1CAM L1 cell adhesion molecule
LAMP3 lysosomal-associated membrane protein 3
MYRF myelin regulatory factor
NMU neuromedin U
OLFM1 olfactomedin 1
OXA1L oxidase (cytochrome c) assembly 1-like
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PGC progastricsin (pepsinogen C)
PPIF peptidylprolyl isomerase F
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
S100A2 S100 calcium binding protein A2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TREM1 triggering receptor expressed on myeloid cells 1
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADI1 acireductone dioxygenase 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CBR3 carbonyl reductase 3
CD2 CD2 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CNN3 calponin 3, acidic
CXCL12 chemokine (C-X-C motif) ligand 12
ELF5 E74-like factor 5 (ets domain transcription factor)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FBN2 fibrillin 2
FLRT2 fibronectin leucine rich transmembrane protein 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GRAMD3 GRAM domain containing 3
GZMK granzyme K (granzyme 3; tryptase II)
HIST1H4C histone cluster 1, H4c
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
LTF lactotransferrin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP7 microtubule-associated protein 7
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MATN2 matrilin 2
MFAP5 microfibrillar associated protein 5
MFGE8 milk fat globule-EGF factor 8 protein
MMP9 matrix metallopeptidase 9
MPPED2 metallophosphoesterase domain containing 2
MSRA methionine sulfoxide reductase A
NDRG2 NDRG family member 2
OLFM4 olfactomedin 4
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX11A peroxisomal biogenesis factor 11 alpha
PHACTR2 phosphatase and actin regulator 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAGL1 pleiomorphic adenoma gene-like 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSME4 proteasome (prosome, macropain) activator subunit 4
PTCH1 patched 1
QPCT glutaminyl-peptide cyclotransferase
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMPO thymopoietin
TPM1 tropomyosin 1 (alpha)
TRAF5 TNF receptor-associated factor 5
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5