BRD-K19220233_JNK-9L_MCF7_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ALCAM activated leukocyte cell adhesion molecule
CXCL8 chemokine (C-X-C motif) ligand 8
DHCR24 24-dehydrocholesterol reductase
DIAPH2 diaphanous-related formin 2
EIF5A eukaryotic translation initiation factor 5A
FBN1 fibrillin 1
FSTL1 follistatin-like 1
GSTP1 glutathione S-transferase pi 1
IFI6 interferon, alpha-inducible protein 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
LAPTM4B lysosomal protein transmembrane 4 beta
LARS leucyl-tRNA synthetase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MORC4 MORC family CW-type zinc finger 4
PI3 peptidase inhibitor 3, skin-derived
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAGL1 pleiomorphic adenoma gene-like 1
PRAME preferentially expressed antigen in melanoma
QDPR quinoid dihydropteridine reductase
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3YL1 SH3 and SYLF domain containing 1
SLC44A4 solute carrier family 44, member 4
SRPX sushi-repeat containing protein, X-linked
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM45A transmembrane protein 45A
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
CCL5 chemokine (C-C motif) ligand 5
CCNE2 cyclin E2
CCNF cyclin F
CDCA4 cell division cycle associated 4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DLX2 distal-less homeobox 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EIF5 eukaryotic translation initiation factor 5
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER5 immediate early response 5
KYNU kynureninase
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR6 lysophosphatidic acid receptor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NCK1 NCK adaptor protein 1
NFIL3 nuclear factor, interleukin 3 regulated
OSR2 odd-skipped related transciption factor 2
PEG3 paternally expressed 3
RRM2 ribonucleotide reductase M2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMAD7 SMAD family member 7
SOX4 SRY (sex determining region Y)-box 4
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBX3 T-box 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM2D3 TM2 domain containing 3
TRIB3 tribbles pseudokinase 3
TSC22D2 TSC22 domain family, member 2
VEGFA vascular endothelial growth factor A
ZNF217 zinc finger protein 217