BRD-K19220233_JNK-9L_MCF7_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF7_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD6 abhydrolase domain containing 6
CAPN6 calpain 6
CCL20 chemokine (C-C motif) ligand 20
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHN2 chimerin 2
CLEC11A C-type lectin domain family 11, member A
CPM carboxypeptidase M
CRYAB crystallin, alpha B
EIF5A eukaryotic translation initiation factor 5A
FOLR1 folate receptor 1 (adult)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GSAP gamma-secretase activating protein
IFI6 interferon, alpha-inducible protein 6
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LTBP3 latent transforming growth factor beta binding protein 3
MDFIC MyoD family inhibitor domain containing
MET MET proto-oncogene, receptor tyrosine kinase
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDZK1IP1 PDZK1 interacting protein 1
PLBD1 phospholipase B domain containing 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS1 regulator of G-protein signaling 1
RPL39L ribosomal protein L39-like
SEPT10 septin 10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SORD sorbitol dehydrogenase
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBXA2R thromboxane A2 receptor
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
VWA8 von Willebrand factor A domain containing 8

decreased expression

Symbol Name
AREG amphiregulin
BAMBI BMP and activin membrane-bound inhibitor
BMP7 bone morphogenetic protein 7
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
FASTKD5 FAST kinase domains 5
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
IER3 immediate early response 3
JAG1 jagged 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MIR22HG MIR22 host gene
NFIL3 nuclear factor, interleukin 3 regulated
NXN nucleoredoxin
OSR2 odd-skipped related transciption factor 2
PDGFA platelet-derived growth factor alpha polypeptide
PERP PERP, TP53 apoptosis effector
POLR1C polymerase (RNA) I polypeptide C, 30kDa
RAB25 RAB25, member RAS oncogene family
RPP38 ribonuclease P/MRP 38kDa subunit
SESN1 sestrin 1
SLC38A2 solute carrier family 38, member 2
SMAD1 SMAD family member 1
SOX4 SRY (sex determining region Y)-box 4
SPEN spen family transcriptional repressor
TACC2 transforming, acidic coiled-coil containing protein 2
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR3 transforming growth factor, beta receptor III
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOB1 transducer of ERBB2, 1
ZFP36 ZFP36 ring finger protein