BRD-K19220233_JNK-9L_MCF7_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

105 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF7_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD10 ankyrin repeat domain 10
ARL4C ADP-ribosylation factor-like 4C
BCL6 B-cell CLL/lymphoma 6
BECN1 beclin 1, autophagy related
C1RL complement component 1, r subcomponent-like
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL4A6 collagen, type IV, alpha 6
CST1 cystatin SN
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
GGT1 gamma-glutamyltransferase 1
GPX2 glutathione peroxidase 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFNGR1 interferon gamma receptor 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT23 keratin 23, type I
LGALS4 lectin, galactoside-binding, soluble, 4
MMP7 matrix metallopeptidase 7
PRNP prion protein
PTHLH parathyroid hormone-like hormone
PVALB parvalbumin
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SPINK1 serine peptidase inhibitor, Kazal type 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMEM45A transmembrane protein 45A
TRIO trio Rho guanine nucleotide exchange factor
TSTA3 tissue specific transplantation antigen P35B
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
WT1 Wilms tumor 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACSL1 acyl-CoA synthetase long-chain family member 1
ADI1 acireductone dioxygenase 1
ASPA aspartoacylase
ATF5 activating transcription factor 5
CA2 carbonic anhydrase II
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CAV2 caveolin 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPF centromere protein F, 350/400kDa
CENPU centromere protein U
CLCA1 chloride channel accessory 1
COL5A2 collagen, type V, alpha 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EBP emopamil binding protein (sterol isomerase)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ENDOD1 endonuclease domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GALC galactosylceramidase
HBB hemoglobin, beta
HIST1H4C histone cluster 1, H4c
HOXB7 homeobox B7
HOXC10 homeobox C10
HOXC6 homeobox C6
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP5 insulin-like growth factor binding protein 5
LOX lysyl oxidase
LTF lactotransferrin
MPO myeloperoxidase
MUC4 mucin 4, cell surface associated
NEK2 NIMA-related kinase 2
OLFML3 olfactomedin-like 3
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBK PDZ binding kinase
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLP1 proteolipid protein 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRDX2 peroxiredoxin 2
RDX radixin
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SFN stratifin
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STMN1 stathmin 1
STOM stomatin
TFRC transferrin receptor
THAP11 THAP domain containing 11
TMEM255A transmembrane protein 255A
TMEM47 transmembrane protein 47
TMSB15A thymosin beta 15a
TSPYL5 TSPY-like 5
TUBB4B tubulin, beta 4B class IVb
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAT1 vesicle amine transport 1
ZFP36L2 ZFP36 ring finger protein-like 2