BRD-K19220233_JNK-9L_MCF10A_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF10A_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ANXA6 annexin A6
ASPN asporin
BHLHE40 basic helix-loop-helix family, member e40
CDA cytidine deaminase
COL6A1 collagen, type VI, alpha 1
COL6A3 collagen, type VI, alpha 3
CST3 cystatin C
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
FLNB filamin B, beta
FOSL1 FOS-like antigen 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAL histidine ammonia-lyase
HDAC6 histone deacetylase 6
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGFBP7 insulin-like growth factor binding protein 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KDM4B lysine (K)-specific demethylase 4B
LAMC2 laminin, gamma 2
LUM lumican
MLPH melanophilin
MYLK myosin light chain kinase
PCOLCE procollagen C-endopeptidase enhancer
PECAM1 platelet/endothelial cell adhesion molecule 1
RAB13 RAB13, member RAS oncogene family
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM259 transmembrane protein 259
TMSB15A thymosin beta 15a
TOX3 TOX high mobility group box family member 3
TPBG trophoblast glycoprotein

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARID4B AT rich interactive domain 4B (RBP1-like)
BAMBI BMP and activin membrane-bound inhibitor
BTG1 B-cell translocation gene 1, anti-proliferative
CAB39 calcium binding protein 39
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CDK17 cyclin-dependent kinase 17
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CNOT4 CCR4-NOT transcription complex, subunit 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAS Fas cell surface death receptor
FRMD4B FERM domain containing 4B
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GATA6 GATA binding protein 6
HSPA13 heat shock protein 70kDa family, member 13
LPIN1 lipin 1
MED13 mediator complex subunit 13
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
N4BP2L2 NEDD4 binding protein 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NRIP1 nuclear receptor interacting protein 1
PARP2 poly (ADP-ribose) polymerase 2
PDGFA platelet-derived growth factor alpha polypeptide
PLXNC1 plexin C1
PPIB peptidylprolyl isomerase B (cyclophilin B)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFC3 replication factor C (activator 1) 3, 38kDa
RGS2 regulator of G-protein signaling 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPP1 secreted phosphoprotein 1
TGIF1 TGFB-induced factor homeobox 1
VGLL1 vestigial-like family member 1