BRD-K19220233_JNK-9L_LNCAP_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K19220233_JNK-9L_LNCAP_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADAM9 ADAM metallopeptidase domain 9
AGR2 anterior gradient 2
ALG8 ALG8, alpha-1,3-glucosyltransferase
AMIGO2 adhesion molecule with Ig-like domain 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFB complement factor B
CPVL carboxypeptidase, vitellogenic-like
CST3 cystatin C
CYFIP2 cytoplasmic FMR1 interacting protein 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GATA3 GATA binding protein 3
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
IL7R interleukin 7 receptor
KDM3A lysine (K)-specific demethylase 3A
KRT20 keratin 20, type I
LDOC1 leucine zipper, down-regulated in cancer 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MPPED2 metallophosphoesterase domain containing 2
MTMR11 myotubularin related protein 11
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PLS1 plastin 1
PRKCA protein kinase C, alpha
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TMEM47 transmembrane protein 47
TNC tenascin C
TOX3 TOX high mobility group box family member 3
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANGPT1 angiopoietin 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
AUTS2 autism susceptibility candidate 2
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFLAR CASP8 and FADD-like apoptosis regulator
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSRP1 cysteine and glycine-rich protein 1
DCLRE1C DNA cross-link repair 1C
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GAS1 growth arrest-specific 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP4 insulin-like growth factor binding protein 4
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
INSM1 insulinoma-associated 1
JADE2 jade family PHD finger 2
KRT19 keratin 19, type I
LMO4 LIM domain only 4
LUM lumican
MAP7 microtubule-associated protein 7
NFIL3 nuclear factor, interleukin 3 regulated
NR2F6 nuclear receptor subfamily 2, group F, member 6
NXN nucleoredoxin
PEG10 paternally expressed 10
PERP PERP, TP53 apoptosis effector
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RGCC regulator of cell cycle
RHOB ras homolog family member B
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLPI secretory leukocyte peptidase inhibitor
SNCAIP synuclein, alpha interacting protein
SOBP sine oculis binding protein homolog (Drosophila)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGIF1 TGFB-induced factor homeobox 1
TUBA4A tubulin, alpha 4a
ZNF232 zinc finger protein 232
ZNF586 zinc finger protein 586