BRD-K19220233_JNK-9L_LNCAP_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

157 genes differentially expressed following the BRD-K19220233_JNK-9L_LNCAP_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELF2 CUGBP, Elav-like family member 2
CFB complement factor B
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL6 chemokine (C-X-C motif) ligand 6
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FCMR Fc fragment of IgM receptor
FGG fibrinogen gamma chain
FLNA filamin A, alpha
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GBP1 guanylate binding protein 1, interferon-inducible
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
GSTM3 glutathione S-transferase mu 3 (brain)
GSTT1 glutathione S-transferase theta 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
ILK integrin-linked kinase
LDOC1 leucine zipper, down-regulated in cancer 1
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS8 lectin, galactoside-binding, soluble, 8
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MEIS3P1 Meis homeobox 3 pseudogene 1
MMP7 matrix metallopeptidase 7
MSX2 msh homeobox 2
NAMPT nicotinamide phosphoribosyltransferase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OPN3 opsin 3
OXA1L oxidase (cytochrome c) assembly 1-like
PDZK1IP1 PDZK1 interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PPL periplakin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RSL1D1 ribosomal L1 domain containing 1
RTN2 reticulon 2
SCG5 secretogranin V
SDC2 syndecan 2
SELENBP1 selenium binding protein 1
SIRT3 sirtuin 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOD2 superoxide dismutase 2, mitochondrial
SPTSSA serine palmitoyltransferase, small subunit A
SQSTM1 sequestosome 1
TBX3 T-box 3
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPP1 tripeptidyl peptidase I
TXNRD1 thioredoxin reductase 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
YPEL5 yippee-like 5 (Drosophila)
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ANKRD36B ankyrin repeat domain 36B
ARG1 arginase 1
ASF1B anti-silencing function 1B histone chaperone
ASPN asporin
ATF5 activating transcription factor 5
AUTS2 autism susceptibility candidate 2
BACE2 beta-site APP-cleaving enzyme 2
C2CD5 C2 calcium-dependent domain containing 5
CCNA2 cyclin A2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPU centromere protein U
COX7B cytochrome c oxidase subunit VIIb
DEPTOR DEP domain containing MTOR-interacting protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EMP2 epithelial membrane protein 2
ETV1 ets variant 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLDC glycine dehydrogenase (decarboxylating)
HAL histidine ammonia-lyase
HIST1H4C histone cluster 1, H4c
HMGB2 high mobility group box 2
HOXC6 homeobox C6
IGF1R insulin-like growth factor 1 receptor
IL13RA2 interleukin 13 receptor, alpha 2
KIAA0101 KIAA0101
KIAA1033 KIAA1033
KIF20A kinesin family member 20A
MCM6 minichromosome maintenance complex component 6
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NPR3 natriuretic peptide receptor 3
NREP neuronal regeneration related protein
NT5DC2 5'-nucleotidase domain containing 2
PLK1 polo-like kinase 1
PRDX4 peroxiredoxin 4
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RFC2 replication factor C (activator 1) 2, 40kDa
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RNASEH2A ribonuclease H2, subunit A
RRM2 ribonucleotide reductase M2
SCGB2A1 secretoglobin, family 2A, member 1
SEPHS1 selenophosphate synthetase 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SMC4 structural maintenance of chromosomes 4
SPP1 secreted phosphoprotein 1
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STMN1 stathmin 1
TBC1D31 TBC1 domain family, member 31
TCF4 transcription factor 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMSB15A thymosin beta 15a
TOP2A topoisomerase (DNA) II alpha 170kDa
TRMT5 tRNA methyltransferase 5
TSPAN13 tetraspanin 13
ZEB1 zinc finger E-box binding homeobox 1
ZWILCH zwilch kinetochore protein