BRD-K19220233_JNK-9L_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

181 genes differentially expressed following the BRD-K19220233_JNK-9L_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALCAM activated leukocyte cell adhesion molecule
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCHE butyrylcholinesterase
C6ORF62 chromosome 6 open reading frame 62
CCL20 chemokine (C-C motif) ligand 20
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CES1 carboxylesterase 1
DMTF1 cyclin D binding myb-like transcription factor 1
FBXO11 F-box protein 11
GLUD1 glutamate dehydrogenase 1
GMDS GDP-mannose 4,6-dehydratase
GPER1 G protein-coupled estrogen receptor 1
GPM6A glycoprotein M6A
IDS iduronate 2-sulfatase
IGKC immunoglobulin kappa constant
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPL lipoprotein lipase
LTA4H leukotriene A4 hydrolase
LYPD1 LY6/PLAUR domain containing 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MAP1B microtubule-associated protein 1B
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MT1M metallothionein 1M
MX2 MX dynamin-like GTPase 2
NEFH neurofilament, heavy polypeptide
PDLIM3 PDZ and LIM domain 3
PHKB phosphorylase kinase, beta
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB21 RAB21, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
SFTPB surfactant protein B
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYT1 synaptotagmin I
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM47 transmembrane protein 47
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53TG1 TP53 target 1 (non-protein coding)
UROS uroporphyrinogen III synthase

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADM adrenomedullin
AMD1 adenosylmethionine decarboxylase 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
AURKB aurora kinase B
BAG5 BCL2-associated athanogene 5
BAMBI BMP and activin membrane-bound inhibitor
BCL10 B-cell CLL/lymphoma 10
BCL6 B-cell CLL/lymphoma 6
BCOR BCL6 corepressor
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CALML3 calmodulin-like 3
CCL8 chemokine (C-C motif) ligand 8
CCNE2 cyclin E2
CCNF cyclin F
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN2AIP CDKN2A interacting protein
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKS2 CDC28 protein kinase regulatory subunit 2
CLK4 CDC-like kinase 4
CLP1 cleavage and polyadenylation factor I subunit 1
COL15A1 collagen, type XV, alpha 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
E2F3 E2F transcription factor 3
EDN1 endothelin 1
EED embryonic ectoderm development
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5 eukaryotic translation initiation factor 5
EMP1 epithelial membrane protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FASTKD5 FAST kinase domains 5
FBXL12 F-box and leucine-rich repeat protein 12
FBXL14 F-box and leucine-rich repeat protein 14
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GTF2B general transcription factor IIB
H2AFX H2A histone family, member X
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IER5 immediate early response 5
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MAPK6 mitogen-activated protein kinase 6
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MED17 mediator complex subunit 17
MSX1 msh homeobox 1
MTF2 metal response element binding transcription factor 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCK1 NCK adaptor protein 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGDN neuroguidin, EIF4E binding protein
NOP16 NOP16 nucleolar protein
OSR2 odd-skipped related transciption factor 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR1C polymerase (RNA) I polypeptide C, 30kDa
PPIF peptidylprolyl isomerase F
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTRH2 peptidyl-tRNA hydrolase 2
RAD23B RAD23 homolog B (S. cerevisiae)
RBM15 RNA binding motif protein 15
RGS2 regulator of G-protein signaling 2
RLF rearranged L-myc fusion
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSBN1 round spermatid basic protein 1
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNRK SNF related kinase
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2
TBX3 T-box 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBR3 transforming growth factor, beta receptor III
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE4 transducin-like enhancer of split 4
TMEM70 transmembrane protein 70
TOB2 transducer of ERBB2, 2
TSC22D2 TSC22 domain family, member 2
TUFT1 tuftelin 1
WEE1 WEE1 G2 checkpoint kinase
XBP1 X-box binding protein 1
ZBED5 zinc finger, BED-type containing 5
ZCCHC2 zinc finger, CCHC domain containing 2
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2