BRD-K19220233_JNK-9L_HS578T_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

136 genes differentially expressed following the BRD-K19220233_JNK-9L_HS578T_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY7 adenylate cyclase 7
ADK adenosine kinase
AKR1C2 aldo-keto reductase family 1, member C2
BIN1 bridging integrator 1
CA2 carbonic anhydrase II
CAV2 caveolin 2
CCND2 cyclin D2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHRDL1 chordin-like 1
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
DAPK1 death-associated protein kinase 1
DES desmin
DMD dystrophin
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF5A eukaryotic translation initiation factor 5A
FAM120A family with sequence similarity 120A
GMDS GDP-mannose 4,6-dehydratase
GPM6A glycoprotein M6A
GPX3 glutathione peroxidase 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HMGA1 high mobility group AT-hook 1
ITM2A integral membrane protein 2A
LPL lipoprotein lipase
MALL mal, T-cell differentiation protein-like
MAOA monoamine oxidase A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
MT1M metallothionein 1M
MYLK myosin light chain kinase
NLRP2 NLR family, pyrin domain containing 2
NT5E 5'-nucleotidase, ecto (CD73)
POSTN periostin, osteoblast specific factor
PPAP2C phosphatidic acid phosphatase type 2C
PSPH phosphoserine phosphatase
QKI QKI, KH domain containing, RNA binding
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SORBS2 sorbin and SH3 domain containing 2
SRPX sushi-repeat containing protein, X-linked
STAP2 signal transducing adaptor family member 2
SYNM synemin, intermediate filament protein
TFPI2 tissue factor pathway inhibitor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM47 transmembrane protein 47
TPD52 tumor protein D52
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ADM adrenomedullin
AHR aryl hydrocarbon receptor
ARL4C ADP-ribosylation factor-like 4C
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CCNE2 cyclin E2
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA4 cell division cycle associated 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHD1 chromodomain helicase DNA binding protein 1
CLU clusterin
COIL coilin
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FASTKD5 FAST kinase domains 5
FZD2 frizzled class receptor 2
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
GSTA1 glutathione S-transferase alpha 1
H2AFX H2A histone family, member X
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H4C histone cluster 1, H4c
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KLF6 Kruppel-like factor 6
KRT15 keratin 15, type I
KRT6B keratin 6B, type II
LRP2 low density lipoprotein receptor-related protein 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MED17 mediator complex subunit 17
MSRA methionine sulfoxide reductase A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFM neurofilament, medium polypeptide
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOP56 NOP56 ribonucleoprotein
PAIP1 poly(A) binding protein interacting protein 1
POLR1C polymerase (RNA) I polypeptide C, 30kDa
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RLF rearranged L-myc fusion
RRM2 ribonucleotide reductase M2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SGK1 serum/glucocorticoid regulated kinase 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
SNRPE small nuclear ribonucleoprotein polypeptide E
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR3 transforming growth factor, beta receptor III
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TOB1 transducer of ERBB2, 1
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein
ZFP36L1 ZFP36 ring finger protein-like 1