BRD-K19220233_JNK-9L_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

141 genes differentially expressed following the BRD-K19220233_JNK-9L_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ALCAM activated leukocyte cell adhesion molecule
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
CCL20 chemokine (C-C motif) ligand 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFD complement factor D (adipsin)
COL3A1 collagen, type III, alpha 1
CPE carboxypeptidase E
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF5A eukaryotic translation initiation factor 5A
FRZB frizzled-related protein
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GPM6A glycoprotein M6A
GPX3 glutathione peroxidase 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR2 lysophosphatidic acid receptor 2
MALL mal, T-cell differentiation protein-like
MAOA monoamine oxidase A
MEF2C myocyte enhancer factor 2C
MT1F metallothionein 1F
MT1M metallothionein 1M
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NMU neuromedin U
NPTX2 neuronal pentraxin II
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGAM1 phosphoglycerate mutase 1 (brain)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLVAP plasmalemma vesicle associated protein
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
RNF130 ring finger protein 130
S100P S100 calcium binding protein P
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SST somatostatin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TMEM45A transmembrane protein 45A
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ADM adrenomedullin
AHR aryl hydrocarbon receptor
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
BCL10 B-cell CLL/lymphoma 10
BTG1 B-cell translocation gene 1, anti-proliferative
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CCNF cyclin F
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIC2 cysteine-rich hydrophobic domain 2
CSTA cystatin A (stefin A)
CXCL11 chemokine (C-X-C motif) ligand 11
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DEPTOR DEP domain containing MTOR-interacting protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP10 dual specificity phosphatase 10
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
GCH1 GTP cyclohydrolase 1
GMNN geminin, DNA replication inhibitor
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HOXA10 homeobox A10
HOXA5 homeobox A5
HSPA13 heat shock protein 70kDa family, member 13
HSPH1 heat shock 105kDa/110kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IER5 immediate early response 5
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
KRT15 keratin 15, type I
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MED17 mediator complex subunit 17
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
NCK1 NCK adaptor protein 1
NFIL3 nuclear factor, interleukin 3 regulated
NUP98 nucleoporin 98kDa
NXT1 nuclear transport factor 2-like export factor 1
PDGFA platelet-derived growth factor alpha polypeptide
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTN pleiotrophin
RBM15 RNA binding motif protein 15
RIN2 Ras and Rab interactor 2
RLF rearranged L-myc fusion
RNH1 ribonuclease/angiogenin inhibitor 1
RPP38 ribonuclease P/MRP 38kDa subunit
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOCS5 suppressor of cytokine signaling 5
SOX4 SRY (sex determining region Y)-box 4
TBX3 T-box 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR4 toll-like receptor 4
TOB1 transducer of ERBB2, 1
TRIM32 tripartite motif containing 32
TSC22D2 TSC22 domain family, member 2
VEGFA vascular endothelial growth factor A
WEE1 WEE1 G2 checkpoint kinase
XBP1 X-box binding protein 1
ZBTB18 zinc finger and BTB domain containing 18
ZFAND5 zinc finger, AN1-type domain 5
ZFP36L2 ZFP36 ring finger protein-like 2