BRD-K19220233_JNK-9L_HS578T_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K19220233_JNK-9L_HS578T_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AKAP8L A kinase (PRKA) anchor protein 8-like
APLP2 amyloid beta (A4) precursor-like protein 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL13 chemokine (C-X-C motif) ligand 13
DSTN destrin (actin depolymerizing factor)
EIF5A eukaryotic translation initiation factor 5A
FAM120A family with sequence similarity 120A
FGFR2 fibroblast growth factor receptor 2
FOXF1 forkhead box F1
IDS iduronate 2-sulfatase
IGHM immunoglobulin heavy constant mu
LIMCH1 LIM and calponin homology domains 1
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MAP7 microtubule-associated protein 7
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NRGN neurogranin (protein kinase C substrate, RC3)
P4HB prolyl 4-hydroxylase, beta polypeptide
PLVAP plasmalemma vesicle associated protein
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TIMP3 TIMP metallopeptidase inhibitor 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
ADM adrenomedullin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL4C ADP-ribosylation factor-like 4C
BAMBI BMP and activin membrane-bound inhibitor
BTG3 BTG family, member 3
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADR coxsackie virus and adenovirus receptor
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EED embryonic ectoderm development
EGR2 early growth response 2
EIF5 eukaryotic translation initiation factor 5
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCH1 GTP cyclohydrolase 1
GPNMB glycoprotein (transmembrane) nmb
GTPBP8 GTP-binding protein 8 (putative)
HMOX1 heme oxygenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IL1R2 interleukin 1 receptor, type II
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KLF11 Kruppel-like factor 11
KRT15 keratin 15, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LAMA3 laminin, alpha 3
LDLR low density lipoprotein receptor
LPIN1 lipin 1
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYH10 myosin, heavy chain 10, non-muscle
NAMPT nicotinamide phosphoribosyltransferase
NELL2 NEL-like 2 (chicken)
NFIL3 nuclear factor, interleukin 3 regulated
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PI3 peptidase inhibitor 3, skin-derived
PLK2 polo-like kinase 2
PTN pleiotrophin
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RIN2 Ras and Rab interactor 2
RRM2 ribonucleotide reductase M2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOX4 SRY (sex determining region Y)-box 4
SPP1 secreted phosphoprotein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TRIB2 tribbles pseudokinase 2
XBP1 X-box binding protein 1
ZNF131 zinc finger protein 131
ZNF217 zinc finger protein 217