BRD-K19220233_JNK-9L_HS578T_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

166 genes differentially expressed following the BRD-K19220233_JNK-9L_HS578T_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADD3 adducin 3 (gamma)
ADGRG2 adhesion G protein-coupled receptor G2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD10 ankyrin repeat domain 10
ASCL1 achaete-scute family bHLH transcription factor 1
C3 complement component 3
CALML4 calmodulin-like 4
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
CDCP1 CUB domain containing protein 1
CLGN calmegin
COL11A1 collagen, type XI, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FAP fibroblast activation protein, alpha
FOLR1 folate receptor 1 (adult)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KIF14 kinesin family member 14
LEF1 lymphoid enhancer-binding factor 1
LOX lysyl oxidase
LRRC59 leucine rich repeat containing 59
MARCKS myristoylated alanine-rich protein kinase C substrate
MSMB microseminoprotein, beta-
NELL2 NEL-like 2 (chicken)
NQO1 NAD(P)H dehydrogenase, quinone 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDE4DIP phosphodiesterase 4D interacting protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP prolactin-induced protein
PSPH phosphoserine phosphatase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASA4 RAS p21 protein activator 4
RGS10 regulator of G-protein signaling 10
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
RUNX3 runt-related transcription factor 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SLAMF7 SLAM family member 7
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TFPI2 tissue factor pathway inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TM9SF3 transmembrane 9 superfamily member 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM260 transmembrane protein 260
TRAPPC6A trafficking protein particle complex 6A
TXNIP thioredoxin interacting protein
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGAP29 Rho GTPase activating protein 29
ATF3 activating transcription factor 3
ATF5 activating transcription factor 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AUTS2 autism susceptibility candidate 2
BGN biglycan
C1QA complement component 1, q subcomponent, A chain
C8ORF4 chromosome 8 open reading frame 4
CADM1 cell adhesion molecule 1
CALR calreticulin
CBS cystathionine-beta-synthase
CD14 CD14 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHL1 cell adhesion molecule L1-like
CSRP1 cysteine and glycine-rich protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
DOK5 docking protein 5
EDN1 endothelin 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ENAH enabled homolog (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP3 fatty acid binding protein 3, muscle and heart
FAIM Fas apoptotic inhibitory molecule
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GADD45B growth arrest and DNA-damage-inducible, beta
GTPBP8 GTP-binding protein 8 (putative)
H2AFV H2A histone family, member V
HIST1H4C histone cluster 1, H4c
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
HOXC10 homeobox C10
HOXC6 homeobox C6
ICAM2 intercellular adhesion molecule 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IGSF3 immunoglobulin superfamily, member 3
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IPW imprinted in Prader-Willi syndrome (non-protein coding)
JCHAIN joining chain of multimeric IgA and IgM
JUND jun D proto-oncogene
JUP junction plakoglobin
KIF2C kinesin family member 2C
LDLR low density lipoprotein receptor
MAP7 microtubule-associated protein 7
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MEG3 maternally expressed 3 (non-protein coding)
MEIS2 Meis homeobox 2
MGP matrix Gla protein
MID1 midline 1
MTUS1 microtubule associated tumor suppressor 1
MYH10 myosin, heavy chain 10, non-muscle
NBN nibrin
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PCCB propionyl CoA carboxylase, beta polypeptide
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM1 PDZ and LIM domain 1
PEG3 paternally expressed 3
PFN2 profilin 2
PLBD1 phospholipase B domain containing 1
PLSCR4 phospholipid scramblase 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSD3 pleckstrin and Sec7 domain containing 3
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB15 RAB15, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
RHOB ras homolog family member B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF130 ring finger protein 130
SC5D sterol-C5-desaturase
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SFTPB surfactant protein B
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SOX4 SRY (sex determining region Y)-box 4
SPON2 spondin 2, extracellular matrix protein
SRGN serglycin
STMN1 stathmin 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TCF4 transcription factor 4
THAP11 THAP domain containing 11
TLE4 transducin-like enhancer of split 4
TMSB15A thymosin beta 15a
TOP2A topoisomerase (DNA) II alpha 170kDa
TPM1 tropomyosin 1 (alpha)
TPM4 tropomyosin 4
TYROBP TYRO protein tyrosine kinase binding protein
WASF3 WAS protein family, member 3
ZBED2 zinc finger, BED-type containing 2