BRD-K19220233_JNK-9L_HME1_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K19220233_JNK-9L_HME1_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ARHGAP15 Rho GTPase activating protein 15
ASS1 argininosuccinate synthase 1
CHL1 cell adhesion molecule L1-like
CPE carboxypeptidase E
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GRIA2 glutamate receptor, ionotropic, AMPA 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITM2A integral membrane protein 2A
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
OSBPL10 oxysterol binding protein-like 10
PDZD2 PDZ domain containing 2
PLA2G16 phospholipase A2, group XVI
PLAC8 placenta-specific 8
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RHOBTB3 Rho-related BTB domain containing 3
SCG2 secretogranin II
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TOX thymocyte selection-associated high mobility group box
TSC22D3 TSC22 domain family, member 3
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
BTG2 BTG family, member 2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CDCA4 cell division cycle associated 4
CKAP4 cytoskeleton-associated protein 4
DICER1 dicer 1, ribonuclease type III
DSP desmoplakin
DUSP6 dual specificity phosphatase 6
EIF5 eukaryotic translation initiation factor 5
EPHA3 EPH receptor A3
FASTKD5 FAST kinase domains 5
FERMT1 fermitin family member 1
GPR183 G protein-coupled receptor 183
HES1 hes family bHLH transcription factor 1
HHEX hematopoietically expressed homeobox
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
INHBA inhibin, beta A
JAG1 jagged 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCTD12 potassium channel tetramerization domain containing 12
KRT7 keratin 7, type II
LAMC2 laminin, gamma 2
LMNA lamin A/C
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
MAT2A methionine adenosyltransferase II, alpha
MYC v-myc avian myelocytomatosis viral oncogene homolog
NGRN neugrin, neurite outgrowth associated
PBX3 pre-B-cell leukemia homeobox 3
PPIF peptidylprolyl isomerase F
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SDC4 syndecan 4
SGK1 serum/glucocorticoid regulated kinase 1
SLPI secretory leukocyte peptidase inhibitor
SMAD7 SMAD family member 7
SOX4 SRY (sex determining region Y)-box 4
SPHK1 sphingosine kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TJP2 tight junction protein 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UGCG UDP-glucose ceramide glucosyltransferase