BRD-K19220233_JNK-9L_HME1_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K19220233_JNK-9L_HME1_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
BCHE butyrylcholinesterase
BRCA1 breast cancer 1, early onset
CFI complement factor I
EML3 echinoderm microtubule associated protein like 3
EPCAM epithelial cell adhesion molecule
FGF13 fibroblast growth factor 13
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
IGHMBP2 immunoglobulin mu binding protein 2
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MUC5B mucin 5B, oligomeric mucus/gel-forming
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OBSL1 obscurin-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN1 perilipin 1
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PSPH phosphoserine phosphatase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBP4 retinol binding protein 4, plasma
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SULF1 sulfatase 1
THAP11 THAP domain containing 11
TPD52L1 tumor protein D52-like 1
TWIST1 twist family bHLH transcription factor 1

decreased expression

Symbol Name
ADM adrenomedullin
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
BTG2 BTG family, member 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CD24 CD24 molecule
CDCA4 cell division cycle associated 4
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DUSP6 dual specificity phosphatase 6
EFHD2 EF-hand domain family, member D2
EIF5 eukaryotic translation initiation factor 5
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
HAT1 histone acetyltransferase 1
HMOX1 heme oxygenase 1
IER3 immediate early response 3
JAG1 jagged 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MARCKS myristoylated alanine-rich protein kinase C substrate
MPO myeloperoxidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFH neurofilament, heavy polypeptide
PBX3 pre-B-cell leukemia homeobox 3
PDGFA platelet-derived growth factor alpha polypeptide
PDZK1IP1 PDZK1 interacting protein 1
PFKP phosphofructokinase, platelet
PPAP2B phosphatidic acid phosphatase type 2B
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SDC4 syndecan 4
SLC38A1 solute carrier family 38, member 1
SNAP25 synaptosomal-associated protein, 25kDa
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TXNDC9 thioredoxin domain containing 9
VCL vinculin
ZFP36 ZFP36 ring finger protein
ZNF185 zinc finger protein 185 (LIM domain)