BRD-K19220233_JNK-9L_HEPG2_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K19220233_JNK-9L_HEPG2_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AGR2 anterior gradient 2
CBR3 carbonyl reductase 3
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CTTN cortactin
CXCR4 chemokine (C-X-C motif) receptor 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ITGA6 integrin, alpha 6
KDM5D lysine (K)-specific demethylase 5D
KIAA0100 KIAA0100
KRT17 keratin 17, type I
MMP7 matrix metallopeptidase 7
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
RASA4 RAS p21 protein activator 4
SIK1 salt-inducible kinase 1
SMAD3 SMAD family member 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ADM adrenomedullin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AOX1 aldehyde oxidase 1
CCNB2 cyclin B2
CCNE2 cyclin E2
CDC20 cell division cycle 20
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
FGFR2 fibroblast growth factor receptor 2
FGL2 fibrinogen-like 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSTL1 follistatin-like 1
FXYD2 FXYD domain containing ion transport regulator 2
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
HIST1H4C histone cluster 1, H4c
HOXB2 homeobox B2
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
ITM2A integral membrane protein 2A
KIAA0101 KIAA0101
LGALS3 lectin, galactoside-binding, soluble, 3
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MGP matrix Gla protein
NT5DC2 5'-nucleotidase domain containing 2
NUSAP1 nucleolar and spindle associated protein 1
PEG3 paternally expressed 3
PLAGL1 pleiomorphic adenoma gene-like 1
PTPRC protein tyrosine phosphatase, receptor type, C
PTTG1 pituitary tumor-transforming 1
RGCC regulator of cell cycle
RPIA ribose 5-phosphate isomerase A
RRM2 ribonucleotide reductase M2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLPI secretory leukocyte peptidase inhibitor
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TMSB15A thymosin beta 15a
TOX thymocyte selection-associated high mobility group box
TUBB2A tubulin, beta 2A class IIa
VAT1 vesicle amine transport 1
ZIC1 Zic family member 1