BRD-K19220233_JNK-9L_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COG7 component of oligomeric golgi complex 7
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
DPYSL2 dihydropyrimidinase-like 2
EMX2 empty spiracles homeobox 2
FOLR1 folate receptor 1 (adult)
GAS6 growth arrest-specific 6
GUSBP3 glucuronidase, beta pseudogene 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IRF8 interferon regulatory factor 8
KIAA0226L KIAA0226-like
LAMP5 lysosomal-associated membrane protein family, member 5
LEPR leptin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MEF2C myocyte enhancer factor 2C
MYO1B myosin IB
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
TCF4 transcription factor 4
TMSB15A thymosin beta 15a

decreased expression

Symbol Name
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CCNE1 cyclin E1
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP5 dual specificity phosphatase 5
FZD7 frizzled class receptor 7
GDF15 growth differentiation factor 15
HOXA10 homeobox A10
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TBX3 T-box 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
WEE1 WEE1 G2 checkpoint kinase
ZFP36 ZFP36 ring finger protein