BRD-K19220233_JNK-9L_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
ADIRF adipogenesis regulatory factor
ALCAM activated leukocyte cell adhesion molecule
AMDHD2 amidohydrolase domain containing 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CXADR coxsackie virus and adenovirus receptor
DKK1 dickkopf WNT signaling pathway inhibitor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0226L KIAA0226-like
MME membrane metallo-endopeptidase
MYH11 myosin, heavy chain 11, smooth muscle
PRKCB protein kinase C, beta
PRUNE2 prune homolog 2 (Drosophila)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
STEAP1 six transmembrane epithelial antigen of the prostate 1
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ATF3 activating transcription factor 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD69 CD69 molecule
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP2 dual specificity phosphatase 2
EIF4A1 eukaryotic translation initiation factor 4A1
EZR ezrin
FNDC3B fibronectin type III domain containing 3B
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IER2 immediate early response 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MTSS1 metastasis suppressor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PROM1 prominin 1
RGCC regulator of cell cycle
RHOB ras homolog family member B
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOB1 transducer of ERBB2, 1
ZFP36 ZFP36 ring finger protein