BRD-K19220233_JNK-9L_BT20_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

131 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKRD10 ankyrin repeat domain 10
AQP4 aquaporin 4
ARG1 arginase 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BEX1 brain expressed, X-linked 1
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CALB1 calbindin 1, 28kDa
CBR3 carbonyl reductase 3
CD44 CD44 molecule (Indian blood group)
COL15A1 collagen, type XV, alpha 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
EGF epidermal growth factor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
ETNK1 ethanolamine kinase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM107A family with sequence similarity 107, member A
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GDF15 growth differentiation factor 15
GNPDA1 glucosamine-6-phosphate deaminase 1
GPC3 glypican 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOPX HOP homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IRS2 insulin receptor substrate 2
JAM2 junctional adhesion molecule 2
KDM5D lysine (K)-specific demethylase 5D
KNG1 kininogen 1
LIF leukemia inhibitory factor
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK9 mitogen-activated protein kinase 9
MLPH melanophilin
MOXD1 monooxygenase, DBH-like 1
NOVA1 neuro-oncological ventral antigen 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PEG3 paternally expressed 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
RPIA ribose 5-phosphate isomerase A
RPS4Y1 ribosomal protein S4, Y-linked 1
RSL1D1 ribosomal L1 domain containing 1
SFN stratifin
SFTPA2 surfactant protein A2
SLC35F2 solute carrier family 35, member F2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPARCL1 SPARC-like 1 (hevin)
SPRY2 sprouty homolog 2 (Drosophila)
STX3 syntaxin 3
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TDO2 tryptophan 2,3-dioxygenase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TRAPPC6A trafficking protein particle complex 6A
TSPAN3 tetraspanin 3
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
TYRP1 tyrosinase-related protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UFM1 ubiquitin-fold modifier 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADI1 acireductone dioxygenase 1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
C4ORF19 chromosome 4 open reading frame 19
CALD1 caldesmon 1
CD200 CD200 molecule
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDA cytidine deaminase
CEP70 centrosomal protein 70kDa
CRIP2 cysteine-rich protein 2
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
GTPBP8 GTP-binding protein 8 (putative)
HBD hemoglobin, delta
HSPB1 heat shock 27kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGSF3 immunoglobulin superfamily, member 3
JCHAIN joining chain of multimeric IgA and IgM
LGALS1 lectin, galactoside-binding, soluble, 1
LOC100505650 uncharacterized LOC100505650
LOX lysyl oxidase
MAPK13 mitogen-activated protein kinase 13
NDRG1 N-myc downstream regulated 1
NNMT nicotinamide N-methyltransferase
NXN nucleoredoxin
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLSCR3 phospholipid scramblase 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCD protein kinase C, delta
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBPMS RNA binding protein with multiple splicing
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC2 syndecan 2
STMN1 stathmin 1
STOM stomatin
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMSB15A thymosin beta 15a
TPM1 tropomyosin 1 (alpha)
TRAF5 TNF receptor-associated factor 5
TSPAN13 tetraspanin 13
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
XIST X inactive specific transcript (non-protein coding)