BRD-K19220233_JNK-9L_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

203 genes differentially expressed following the BRD-K19220233_JNK-9L_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ALB albumin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMBP alpha-1-microglobulin/bikunin precursor
APOC2 apolipoprotein C-II
APOLD1 apolipoprotein L domain containing 1
AQP1 aquaporin 1 (Colton blood group)
ASPN asporin
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BHLHE40 basic helix-loop-helix family, member e40
BHMT2 betaine--homocysteine S-methyltransferase 2
BIRC3 baculoviral IAP repeat containing 3
BST2 bone marrow stromal cell antigen 2
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CAV1 caveolin 1, caveolae protein, 22kDa
CCL4 chemokine (C-C motif) ligand 4
CCL8 chemokine (C-C motif) ligand 8
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD93 CD93 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CFI complement factor I
CLEC3B C-type lectin domain family 3, member B
CPE carboxypeptidase E
CPVL carboxypeptidase, vitellogenic-like
CRISP3 cysteine-rich secretory protein 3
CTSO cathepsin O
CXCL10 chemokine (C-X-C motif) ligand 10
CYBRD1 cytochrome b reductase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DLX2 distal-less homeobox 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXPH5 exophilin 5
FBLN1 fibulin 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF13 fibroblast growth factor 13
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FXYD3 FXYD domain containing ion transport regulator 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA2 GATA binding protein 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GC group-specific component (vitamin D binding protein)
GHR growth hormone receptor
GLUL glutamate-ammonia ligase
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GPX1 glutathione peroxidase 1
GSTM3 glutathione S-transferase mu 3 (brain)
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HBE1 hemoglobin, epsilon 1
HIST1H1C histone cluster 1, H1c
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IFI30 interferon, gamma-inducible protein 30
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6 interleukin 6
ISG15 ISG15 ubiquitin-like modifier
JAM2 junctional adhesion molecule 2
LAMP1 lysosomal-associated membrane protein 1
LEF1 lymphoid enhancer-binding factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1C1 mannosidase, alpha, class 1C, member 1
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MPPED2 metallophosphoesterase domain containing 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
NGRN neugrin, neurite outgrowth associated
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPTN optineurin
ORM1 orosomucoid 1
PEG3 paternally expressed 3
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLAT plasminogen activator, tissue
PRDX2 peroxiredoxin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RPL31 ribosomal protein L31
RPS5 ribosomal protein S5
SATB1 SATB homeobox 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN1 sestrin 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SORD sorbitol dehydrogenase
SPARCL1 SPARC-like 1 (hevin)
SSBP2 single-stranded DNA binding protein 2
SSPN sarcospan
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TACSTD2 tumor-associated calcium signal transducer 2
TF transferrin
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TJP2 tight junction protein 2
TKTL1 transketolase-like 1
TMOD1 tropomodulin 1
TMPRSS3 transmembrane protease, serine 3
TMSB15A thymosin beta 15a
TSPAN7 tetraspanin 7
VWA5A von Willebrand factor A domain containing 5A
ZMAT3 zinc finger, matrin-type 3
ZNF264 zinc finger protein 264
ZNF91 zinc finger protein 91
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
BLMH bleomycin hydrolase
C3ORF14 chromosome 3 open reading frame 14
CANT1 calcium activated nucleotidase 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCNB2 cyclin B2
CDC25B cell division cycle 25B
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CTBP2 C-terminal binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL2 dihydropyrimidinase-like 2
ECD ecdysoneless homolog (Drosophila)
ECT2 epithelial cell transforming 2
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLOD4 glyoxalase domain containing 4
H1F0 H1 histone family, member 0
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
LXN latexin
MALL mal, T-cell differentiation protein-like
MAP7 microtubule-associated protein 7
MED1 mediator complex subunit 1
MELK maternal embryonic leucine zipper kinase
MTUS1 microtubule associated tumor suppressor 1
NUP85 nucleoporin 85kDa
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBK PDZ binding kinase
PLCB4 phospholipase C, beta 4
PMM2 phosphomannomutase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RAB4A RAB4A, member RAS oncogene family
RFC3 replication factor C (activator 1) 3, 38kDa
RGS2 regulator of G-protein signaling 2
S100A7 S100 calcium binding protein A7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TMEM5 transmembrane protein 5
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa
TXLNA taxilin alpha
ZNF395 zinc finger protein 395