BRD-K19220233_JNK-9L_A549_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

208 genes differentially expressed following the BRD-K19220233_JNK-9L_A549_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOLD1 apolipoprotein L domain containing 1
AQP1 aquaporin 1 (Colton blood group)
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASPN asporin
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV2 caveolin 2
CD163 CD163 molecule
CD302 CD302 molecule
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CD93 CD93 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP70 centrosomal protein 70kDa
CFB complement factor B
CFI complement factor I
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
COL6A3 collagen, type VI, alpha 3
CPB1 carboxypeptidase B1 (tissue)
CTSO cathepsin O
CXCL10 chemokine (C-X-C motif) ligand 10
CYBRD1 cytochrome b reductase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DST dystonin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
EPAS1 endothelial PAS domain protein 1
F13A1 coagulation factor XIII, A1 polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FBLN1 fibulin 1
FBN1 fibrillin 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FRY furry homolog (Drosophila)
FXYD5 FXYD domain containing ion transport regulator 5
GHR growth hormone receptor
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GPR183 G protein-coupled receptor 183
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
GUK1 guanylate kinase 1
HEG1 heart development protein with EGF-like domains 1
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGA1 high mobility group AT-hook 1
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6 interleukin 6
ISG15 ISG15 ubiquitin-like modifier
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITM2A integral membrane protein 2A
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMP2 lysosomal-associated membrane protein 2
LRRC17 leucine rich repeat containing 17
LY96 lymphocyte antigen 96
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MEF2C myocyte enhancer factor 2C
MEIS2 Meis homeobox 2
MN1 meningioma (disrupted in balanced translocation) 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MXRA7 matrix-remodelling associated 7
MYLK myosin light chain kinase
NMU neuromedin U
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OPTN optineurin
PAM peptidylglycine alpha-amidating monooxygenase
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PFN2 profilin 2
PLAT plasminogen activator, tissue
PODXL podocalyxin-like
PPT1 palmitoyl-protein thioesterase 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
QPRT quinolinate phosphoribosyltransferase
RGS16 regulator of G-protein signaling 16
RHOBTB3 Rho-related BTB domain containing 3
SAMHD1 SAM domain and HD domain 1
SATB1 SATB homeobox 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SSR4 signal sequence receptor, delta
STC1 stanniocalcin 1
SULF1 sulfatase 1
THBS2 thrombospondin 2
TKTL1 transketolase-like 1
TMPRSS3 transmembrane protease, serine 3
TMSB15A thymosin beta 15a
TTC3 tetratricopeptide repeat domain 3
VAT1 vesicle amine transport 1
VGLL1 vestigial-like family member 1
VNN1 vanin 1
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMD1 adenosylmethionine decarboxylase 1
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
AUTS2 autism susceptibility candidate 2
BASP1 brain abundant, membrane attached signal protein 1
BLMH bleomycin hydrolase
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
CANT1 calcium activated nucleotidase 1
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CTBP2 C-terminal binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FBL fibrillarin
GINS1 GINS complex subunit 1 (Psf1 homolog)
GRWD1 glutamate-rich WD repeat containing 1
GSPT2 G1 to S phase transition 2
H1F0 H1 histone family, member 0
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
ILF3 interleukin enhancer binding factor 3, 90kDa
KEAP1 kelch-like ECH-associated protein 1
LRP4 low density lipoprotein receptor-related protein 4
LYZ lysozyme
MARCKSL1 MARCKS-like 1
MED1 mediator complex subunit 1
MREG melanoregulin
MRPS12 mitochondrial ribosomal protein S12
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOP56 NOP56 ribonucleoprotein
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
PCNA proliferating cell nuclear antigen
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RAB4A RAB4A, member RAS oncogene family
RAE1 ribonucleic acid export 1
RFC3 replication factor C (activator 1) 3, 38kDa
RNPS1 RNA binding protein S1, serine-rich domain
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TACC2 transforming, acidic coiled-coil containing protein 2
TARP TCR gamma alternate reading frame protein
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPO thymopoietin
TXLNA taxilin alpha
USP22 ubiquitin specific peptidase 22
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
XBP1 X-box binding protein 1