BRD-K19220233_JNK-9L_A375_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

121 genes differentially expressed following the BRD-K19220233_JNK-9L_A375_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APLP2 amyloid beta (A4) precursor-like protein 2
AREG amphiregulin
ASS1 argininosuccinate synthase 1
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
CCL8 chemokine (C-C motif) ligand 8
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CYCS cytochrome c, somatic
DFNA5 deafness, autosomal dominant 5
ENO2 enolase 2 (gamma, neuronal)
FHL2 four and a half LIM domains 2
GDF15 growth differentiation factor 15
GGT1 gamma-glutamyltransferase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IER5 immediate early response 5
KRT23 keratin 23, type I
MMP7 matrix metallopeptidase 7
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRCAM neuronal cell adhesion molecule
NUP210 nucleoporin 210kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PSAP prosaposin
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RHOD ras homolog family member D
RSL1D1 ribosomal L1 domain containing 1
SCG5 secretogranin V
SLC22A18 solute carrier family 22, member 18
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TFPI2 tissue factor pathway inhibitor 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A
TRIM22 tripartite motif containing 22
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CDK1 cyclin-dependent kinase 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CENPN centromere protein N
CENPU centromere protein U
CLC Charcot-Leyden crystal galectin
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
DEK DEK proto-oncogene
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DOCK4 dedicator of cytokinesis 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FZD7 frizzled class receptor 7
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLRX glutaredoxin (thioltransferase)
GTPBP8 GTP-binding protein 8 (putative)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBB hemoglobin, beta
HIST1H4C histone cluster 1, H4c
HMGB1 high mobility group box 1
HOXB2 homeobox B2
HOXB7 homeobox B7
HOXC10 homeobox C10
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
ITGA6 integrin, alpha 6
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JCHAIN joining chain of multimeric IgA and IgM
KIAA0101 KIAA0101
KLHL9 kelch-like family member 9
MARCKSL1 MARCKS-like 1
MCM5 minichromosome maintenance complex component 5
MGP matrix Gla protein
MX2 MX dynamin-like GTPase 2
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NUAK1 NUAK family, SNF1-like kinase, 1
NUSAP1 nucleolar and spindle associated protein 1
OIP5 Opa interacting protein 5
PCNA proliferating cell nuclear antigen
PLAT plasminogen activator, tissue
PLN phospholamban
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POU2AF1 POU class 2 associating factor 1
RBBP4 retinoblastoma binding protein 4
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCAN1 regulator of calcineurin 1
RIN2 Ras and Rab interactor 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMC4 structural maintenance of chromosomes 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STMN1 stathmin 1
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THAP11 THAP domain containing 11
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TMEM47 transmembrane protein 47
TMPO thymopoietin
TNS3 tensin 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WNT5A wingless-type MMTV integration site family, member 5A
ZWILCH zwilch kinetochore protein