BRD-K18761689_4-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid WFM1.17B_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-K18761689_4-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid WFM1.17B_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ADRB2 adrenoceptor beta 2, surface
AREG amphiregulin
C3 complement component 3
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP6 charged multivesicular body protein 6
CLU clusterin
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CXCR4 chemokine (C-X-C motif) receptor 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EGFL6 EGF-like-domain, multiple 6
EREG epiregulin
FCMR Fc fragment of IgM receptor
FOSL2 FOS-like antigen 2
GREM1 gremlin 1, DAN family BMP antagonist
GULP1 GULP, engulfment adaptor PTB domain containing 1
IL1R1 interleukin 1 receptor, type I
JAG1 jagged 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTBP1 latent transforming growth factor beta binding protein 1
MAPK13 mitogen-activated protein kinase 13
MB myoglobin
MEIS1 Meis homeobox 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NID2 nidogen 2 (osteonidogen)
PDE4DIP phosphodiesterase 4D interacting protein
PEG10 paternally expressed 10
PEG3 paternally expressed 3
RBP1 retinol binding protein 1, cellular
SIK1 salt-inducible kinase 1
THBS1 thrombospondin 1
TMEM110 transmembrane protein 110
TMOD1 tropomodulin 1
TSPYL5 TSPY-like 5
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UPK1B uroplakin 1B
WDR7 WD repeat domain 7
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ANXA1 annexin A1
APP amyloid beta (A4) precursor protein
ATF5 activating transcription factor 5
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD44 CD44 molecule (Indian blood group)
CDCA4 cell division cycle associated 4
CIAPIN1 cytokine induced apoptosis inhibitor 1
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DYNLRB1 dynein, light chain, roadblock-type 1
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
ESD esterase D
EXT1 exostosin glycosyltransferase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPH1 heat shock 105kDa/110kDa protein 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS4 lectin, galactoside-binding, soluble, 4
MBNL2 muscleblind-like splicing regulator 2
NOSIP nitric oxide synthase interacting protein
NRIP1 nuclear receptor interacting protein 1
PCCB propionyl CoA carboxylase, beta polypeptide
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLS3 plastin 3
PRMT1 protein arginine methyltransferase 1
PRNP prion protein
PRPS1 phosphoribosyl pyrophosphate synthetase 1
RNH1 ribonuclease/angiogenin inhibitor 1
RTN2 reticulon 2
S100A10 S100 calcium binding protein A10
SCAND1 SCAN domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDCBP syndecan binding protein (syntenin)
SLC35F2 solute carrier family 35, member F2
SNX10 sorting nexin 10
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STIP1 stress-induced phosphoprotein 1
STK26 serine/threonine protein kinase 26
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TKT transketolase
TM9SF3 transmembrane 9 superfamily member 3
TMEM176B transmembrane protein 176B
TOR1A torsin family 1, member A (torsin A)
TRIP6 thyroid hormone receptor interactor 6
TSPAN4 tetraspanin 4
UBE2S ubiquitin-conjugating enzyme E2S
UFM1 ubiquitin-fold modifier 1
UQCRC2 ubiquinol-cytochrome c reductase core protein II
WDR61 WD repeat domain 61
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1