Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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101 genes differentially expressed following the BRD-K18761689_4-(5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid WFM1.17B_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADAM10 | ADAM metallopeptidase domain 10 |
ADRB2 | adrenoceptor beta 2, surface |
AREG | amphiregulin |
C3 | complement component 3 |
CADM1 | cell adhesion molecule 1 |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CD24 | CD24 molecule |
CD9 | CD9 molecule |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHMP6 | charged multivesicular body protein 6 |
CLU | clusterin |
COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DLK1 | delta-like 1 homolog (Drosophila) |
EGFL6 | EGF-like-domain, multiple 6 |
EREG | epiregulin |
FCMR | Fc fragment of IgM receptor |
FOSL2 | FOS-like antigen 2 |
GREM1 | gremlin 1, DAN family BMP antagonist |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
IL1R1 | interleukin 1 receptor, type I |
JAG1 | jagged 1 |
LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MAPK13 | mitogen-activated protein kinase 13 |
MB | myoglobin |
MEIS1 | Meis homeobox 1 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
NID2 | nidogen 2 (osteonidogen) |
PDE4DIP | phosphodiesterase 4D interacting protein |
PEG10 | paternally expressed 10 |
PEG3 | paternally expressed 3 |
RBP1 | retinol binding protein 1, cellular |
SIK1 | salt-inducible kinase 1 |
THBS1 | thrombospondin 1 |
TMEM110 | transmembrane protein 110 |
TMOD1 | tropomodulin 1 |
TSPYL5 | TSPY-like 5 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
UPK1B | uroplakin 1B |
WDR7 | WD repeat domain 7 |
ZNF331 | zinc finger protein 331 |
Symbol | Name |
---|---|
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
ANXA1 | annexin A1 |
APP | amyloid beta (A4) precursor protein |
ATF5 | activating transcription factor 5 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BAG3 | BCL2-associated athanogene 3 |
CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
CD44 | CD44 molecule (Indian blood group) |
CDCA4 | cell division cycle associated 4 |
CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
CSRP1 | cysteine and glycine-rich protein 1 |
CSRP2 | cysteine and glycine-rich protein 2 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DYNLRB1 | dynein, light chain, roadblock-type 1 |
EMP3 | epithelial membrane protein 3 |
ENO1 | enolase 1, (alpha) |
ESD | esterase D |
EXT1 | exostosin glycosyltransferase 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LGALS4 | lectin, galactoside-binding, soluble, 4 |
MBNL2 | muscleblind-like splicing regulator 2 |
NOSIP | nitric oxide synthase interacting protein |
NRIP1 | nuclear receptor interacting protein 1 |
PCCB | propionyl CoA carboxylase, beta polypeptide |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
PLS3 | plastin 3 |
PRMT1 | protein arginine methyltransferase 1 |
PRNP | prion protein |
PRPS1 | phosphoribosyl pyrophosphate synthetase 1 |
RNH1 | ribonuclease/angiogenin inhibitor 1 |
RTN2 | reticulon 2 |
S100A10 | S100 calcium binding protein A10 |
SCAND1 | SCAN domain containing 1 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SDCBP | syndecan binding protein (syntenin) |
SLC35F2 | solute carrier family 35, member F2 |
SNX10 | sorting nexin 10 |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
STIP1 | stress-induced phosphoprotein 1 |
STK26 | serine/threonine protein kinase 26 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TKT | transketolase |
TM9SF3 | transmembrane 9 superfamily member 3 |
TMEM176B | transmembrane protein 176B |
TOR1A | torsin family 1, member A (torsin A) |
TRIP6 | thyroid hormone receptor interactor 6 |
TSPAN4 | tetraspanin 4 |
UBE2S | ubiquitin-conjugating enzyme E2S |
UFM1 | ubiquitin-fold modifier 1 |
UQCRC2 | ubiquinol-cytochrome c reductase core protein II |
WDR61 | WD repeat domain 61 |
YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |