BRD-K18724229_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K18724229_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AQP3 aquaporin 3 (Gill blood group)
ARHGAP29 Rho GTPase activating protein 29
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
C7 complement component 7
CD52 CD52 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLU clusterin
CTSV cathepsin V
DDB2 damage-specific DNA binding protein 2, 48kDa
DHRS2 dehydrogenase/reductase (SDR family) member 2
ERMP1 endoplasmic reticulum metallopeptidase 1
FGF13 fibroblast growth factor 13
FRY furry homolog (Drosophila)
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
H3F3B H3 histone, family 3B (H3.3B)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INSIG1 insulin induced gene 1
KRT13 keratin 13, type I
KRT17 keratin 17, type I
LDLR low density lipoprotein receptor
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MVP major vault protein
MYO6 myosin VI
NR4A2 nuclear receptor subfamily 4, group A, member 2
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRDX2 peroxiredoxin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SGK1 serum/glucocorticoid regulated kinase 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
CA12 carbonic anhydrase XII
CANT1 calcium activated nucleotidase 1
CCNA2 cyclin A2
CCND1 cyclin D1
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CLC Charcot-Leyden crystal galectin
CPE carboxypeptidase E
CRTAP cartilage associated protein
DCK deoxycytidine kinase
DCXR dicarbonyl/L-xylulose reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
EXOSC4 exosome component 4
FAM69A family with sequence similarity 69, member A
FKBP11 FK506 binding protein 11, 19 kDa
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIF20A kinesin family member 20A
MLPH melanophilin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NET1 neuroepithelial cell transforming 1
NUP62 nucleoporin 62kDa
PRR7 proline rich 7 (synaptic)
PTX3 pentraxin 3, long
REG3A regenerating islet-derived 3 alpha
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPDEF SAM pointed domain containing ETS transcription factor
STC2 stanniocalcin 2
STRA13 stimulated by retinoic acid 13
TRIP13 thyroid hormone receptor interactor 13
UBE2C ubiquitin-conjugating enzyme E2C