BRD-K18724229_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

311 genes differentially expressed following the BRD-K18724229_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACAA1 acetyl-CoA acyltransferase 1
ACKR3 atypical chemokine receptor 3
ACSL1 acyl-CoA synthetase long-chain family member 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
AGR2 anterior gradient 2
AMIGO2 adhesion molecule with Ig-like domain 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP29 Rho GTPase activating protein 29
ASPN asporin
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BASP1 brain abundant, membrane attached signal protein 1
BECN1 beclin 1, autophagy related
BIK BCL2-interacting killer (apoptosis-inducing)
BLCAP bladder cancer associated protein
BLNK B-cell linker
BSG basigin (Ok blood group)
BTG2 BTG family, member 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA2 carbonic anhydrase II
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPG capping protein (actin filament), gelsolin-like
CBR3 carbonyl reductase 3
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CD9 CD9 molecule
CDC25B cell division cycle 25B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK19 cyclin-dependent kinase 19
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNR1 cannabinoid receptor 1 (brain)
COG4 component of oligomeric golgi complex 4
COL10A1 collagen, type X, alpha 1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSA cathepsin A
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
EMC3 ER membrane protein complex subunit 3
EMP1 epithelial membrane protein 1
EPS8 epidermal growth factor receptor pathway substrate 8
EZR ezrin
FABP4 fatty acid binding protein 4, adipocyte
FBP1 fructose-1,6-bisphosphatase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FN1 fibronectin 1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FST follistatin
FUCA1 fucosidase, alpha-L- 1, tissue
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FZD7 frizzled class receptor 7
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GLA galactosidase, alpha
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GOLGA8A golgin A8 family, member A
GOLM1 golgi membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB10 growth factor receptor-bound protein 10
GREM1 gremlin 1, DAN family BMP antagonist
GUSBP11 glucuronidase, beta pseudogene 11
H3F3B H3 histone, family 3B (H3.3B)
HEBP1 heme binding protein 1
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HOMER3 homer scaffolding protein 3
HOPX HOP homeobox
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPB1 heat shock 27kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LAMP1 lysosomal-associated membrane protein 1
LIMA1 LIM domain and actin binding 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LPIN1 lipin 1
LPXN leupaxin
LRP10 low density lipoprotein receptor-related protein 10
LRRC15 leucine rich repeat containing 15
LSR lipolysis stimulated lipoprotein receptor
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCOLN1 mucolipin 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIR22HG MIR22 host gene
MXRA5 matrix-remodelling associated 5
MYO6 myosin VI
NBPF10 neuroblastoma breakpoint family, member 10
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP1 nuclear receptor interacting protein 1
NTAN1 N-terminal asparagine amidase
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX1 pre-B-cell leukemia homeobox 1
PHYH phytanoyl-CoA 2-hydroxylase
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PINK1 PTEN induced putative kinase 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
POU2AF1 POU class 2 associating factor 1
PRKCD protein kinase C, delta
PROM1 prominin 1
PSCA prostate stem cell antigen
RAD9A RAD9 homolog A (S. pombe)
RAP1GAP RAP1 GTPase activating protein
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRAGC Ras-related GTP binding C
S100A13 S100 calcium binding protein A13
S100A8 S100 calcium binding protein A8
SAP18 Sin3A-associated protein, 18kDa
SAT1 spermidine/spermine N1-acetyltransferase 1
SC5D sterol-C5-desaturase
SDCBP syndecan binding protein (syntenin)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SST somatostatin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17A serine/threonine kinase 17a
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TAGLN transgelin
TIMP3 TIMP metallopeptidase inhibitor 3
TLE4 transducin-like enhancer of split 4
TOX3 TOX high mobility group box family member 3
TSC22D1 TSC22 domain family, member 1
TSC22D2 TSC22 domain family, member 2
TSC22D3 TSC22 domain family, member 3
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
UBE3B ubiquitin protein ligase E3B
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPK1B uroplakin 1B
VAT1 vesicle amine transport 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACPP acid phosphatase, prostate
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA1 annexin A1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
B3GNT1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C1QBP complement component 1, q subcomponent binding protein
C9ORF16 chromosome 9 open reading frame 16
CCDC85B coiled-coil domain containing 85B
CCDC86 coiled-coil domain containing 86
CCNA2 cyclin A2
CCND1 cyclin D1
CD14 CD14 molecule
CDK4 cyclin-dependent kinase 4
CLNS1A chloride channel, nucleotide-sensitive, 1A
COL1A2 collagen, type I, alpha 2
COL21A1 collagen, type XXI, alpha 1
CRISP3 cysteine-rich secretory protein 3
CRTAP cartilage associated protein
CSRP1 cysteine and glycine-rich protein 1
CTPS1 CTP synthase 1
CTSZ cathepsin Z
CXCL9 chemokine (C-X-C motif) ligand 9
CYCS cytochrome c, somatic
DCK deoxycytidine kinase
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DKC1 dyskeratosis congenita 1, dyskerin
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
EBP emopamil binding protein (sterol isomerase)
EDNRA endothelin receptor type A
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF4B eukaryotic translation initiation factor 4B
EIF5A eukaryotic translation initiation factor 5A
EPRS glutamyl-prolyl-tRNA synthetase
F12 coagulation factor XII (Hageman factor)
FBL fibrillarin
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB2 GRB2-associated binding protein 2
GAS2 growth arrest-specific 2
GCAT glycine C-acetyltransferase
GLTSCR2 glioma tumor suppressor candidate region gene 2
GPI glucose-6-phosphate isomerase
GPM6B glycoprotein M6B
GREB1 growth regulation by estrogen in breast cancer 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOMER2 homer scaffolding protein 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
IARS isoleucyl-tRNA synthetase
IFRD2 interferon-related developmental regulator 2
IGF1R insulin-like growth factor 1 receptor
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
ITM2A integral membrane protein 2A
KIAA0101 KIAA0101
KLK2 kallikrein-related peptidase 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYPLA1 lysophospholipase I
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MME membrane metallo-endopeptidase
MRPL12 mitochondrial ribosomal protein L12
MRPL15 mitochondrial ribosomal protein L15
MRPL24 mitochondrial ribosomal protein L24
MRPS12 mitochondrial ribosomal protein S12
MRPS2 mitochondrial ribosomal protein S2
MSLN mesothelin
MUC16 mucin 16, cell surface associated
MYBPC1 myosin binding protein C, slow type
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NCAPD3 non-SMC condensin II complex, subunit D3
NCK1 NCK adaptor protein 1
NEFH neurofilament, heavy polypeptide
NELL2 NEL-like 2 (chicken)
NHP2 NHP2 ribonucleoprotein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPM3 nucleophosmin/nucleoplasmin 3
NUP62 nucleoporin 62kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAK1IP1 PAK1 interacting protein 1
PARVB parvin, beta
PBK PDZ binding kinase
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PFKP phosphofructokinase, platelet
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPA1 pyrophosphatase (inorganic) 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRAME preferentially expressed antigen in melanoma
PRDX4 peroxiredoxin 4
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PUS7 pseudouridylate synthase 7 (putative)
RAB4A RAB4A, member RAS oncogene family
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RIPK2 receptor-interacting serine-threonine kinase 2
RLN1 relaxin 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL14 ribosomal protein L14
RPL22 ribosomal protein L22
RPL31 ribosomal protein L31
RPL35 ribosomal protein L35
RPS2 ribosomal protein S2
RPS4Y1 ribosomal protein S4, Y-linked 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCARB1 scavenger receptor class B, member 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SORD sorbitol dehydrogenase
SRM spermidine synthase
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNGR2 synaptogyrin 2
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM109 transmembrane protein 109
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TRIP13 thyroid hormone receptor interactor 13
TSPAN8 tetraspanin 8
TUBB tubulin, beta class I
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UXT ubiquitously-expressed, prefoldin-like chaperone
VARS valyl-tRNA synthetase
WDR12 WD repeat domain 12