BRD-K18724229_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K18724229_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CCDC92 coiled-coil domain containing 92
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EREG epiregulin
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
IGFBP4 insulin-like growth factor binding protein 4
LGALS1 lectin, galactoside-binding, soluble, 1
MAP7 microtubule-associated protein 7
NPY neuropeptide Y
NRIP1 nuclear receptor interacting protein 1
OSBPL10 oxysterol binding protein-like 10
PDZK1IP1 PDZK1 interacting protein 1
PLK2 polo-like kinase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RUNX3 runt-related transcription factor 3
SPON1 spondin 1, extracellular matrix protein
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TBX3 T-box 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASPH aspartate beta-hydroxylase
BAG3 BCL2-associated athanogene 3
C3 complement component 3
CD200 CD200 molecule
CFD complement factor D (adipsin)
CFI complement factor I
CSRP2 cysteine and glycine-rich protein 2
DSG2 desmoglein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
KRT15 keratin 15, type I
LAPTM5 lysosomal protein transmembrane 5
LOX lysyl oxidase
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
RDX radixin
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4