BRD-K18724229_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K18724229_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATF5 activating transcription factor 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL4A5 collagen, type IV, alpha 5
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDB2 damage-specific DNA binding protein 2, 48kDa
FILIP1L filamin A interacting protein 1-like
FZD5 frizzled class receptor 5
GDF15 growth differentiation factor 15
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSDL2 hydroxysteroid dehydrogenase like 2
MOSPD1 motile sperm domain containing 1
PRKCI protein kinase C, iota
S100A9 S100 calcium binding protein A9
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SESN1 sestrin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
TRIM22 tripartite motif containing 22
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
AARS alanyl-tRNA synthetase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANXA1 annexin A1
BEX1 brain expressed, X-linked 1
CD59 CD59 molecule, complement regulatory protein
CDCA4 cell division cycle associated 4
FOSL1 FOS-like antigen 1
FXYD3 FXYD domain containing ion transport regulator 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HEATR1 HEAT repeat containing 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
KRT6A keratin 6A, type II
KRT7 keratin 7, type II
MMP7 matrix metallopeptidase 7
NME4 NME/NM23 nucleoside diphosphate kinase 4
NRCAM neuronal cell adhesion molecule
PSPH phosphoserine phosphatase
SCAND1 SCAN domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
THBS4 thrombospondin 4
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
VCAM1 vascular cell adhesion molecule 1
XIST X inactive specific transcript (non-protein coding)