BRD-K18595892_1-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K18595892_1-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGAP29 Rho GTPase activating protein 29
BAG3 BCL2-associated athanogene 3
BZW2 basic leucine zipper and W2 domains 2
COL9A3 collagen, type IX, alpha 3
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EDNRB endothelin receptor type B
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LPL lipoprotein lipase
MGLL monoglyceride lipase
MSMO1 methylsterol monooxygenase 1
NFIB nuclear factor I/B
NSDHL NAD(P) dependent steroid dehydrogenase-like
PPAP2B phosphatidic acid phosphatase type 2B
PTGES prostaglandin E synthase
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPINK5 serine peptidase inhibitor, Kazal type 5
SQLE squalene epoxidase
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL4 chemokine (C-C motif) ligand 4
CD40 CD40 molecule, TNF receptor superfamily member 5
CXCL10 chemokine (C-X-C motif) ligand 10
EIF5A eukaryotic translation initiation factor 5A
HIST1H1C histone cluster 1, H1c
LBH limb bud and heart development
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
PCCB propionyl CoA carboxylase, beta polypeptide
PFKP phosphofructokinase, platelet
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SCG5 secretogranin V
SULF1 sulfatase 1
TRD T cell receptor delta locus
UBE3C ubiquitin protein ligase E3C