BRD-K18595892_1-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K18595892_1-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl}-N-[2-(dipropylamino)ethyl]piperidine-4-carboxamide_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
AREG amphiregulin
CAPG capping protein (actin filament), gelsolin-like
CD14 CD14 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CSTA cystatin A (stefin A)
CYB561 cytochrome b561
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
EGR1 early growth response 1
EGR3 early growth response 3
ELOVL6 ELOVL fatty acid elongase 6
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GCLC glutamate-cysteine ligase, catalytic subunit
GNPDA1 glucosamine-6-phosphate deaminase 1
GRN granulin
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP7 insulin-like growth factor binding protein 7
INSIG1 insulin induced gene 1
JADE2 jade family PHD finger 2
LDLR low density lipoprotein receptor
LIPA lipase A, lysosomal acid, cholesterol esterase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MANSC1 MANSC domain containing 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MB myoglobin
MSMO1 methylsterol monooxygenase 1
NEU1 sialidase 1 (lysosomal sialidase)
NSDHL NAD(P) dependent steroid dehydrogenase-like
PDGFRL platelet-derived growth factor receptor-like
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHYH phytanoyl-CoA 2-hydroxylase
PKM pyruvate kinase, muscle
PROM1 prominin 1
PSPH phosphoserine phosphatase
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXDN peroxidasin
RAP1GAP RAP1 GTPase activating protein
RGS13 regulator of G-protein signaling 13
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
VCAN versican

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AHNAK AHNAK nucleoprotein
AKAP12 A kinase (PRKA) anchor protein 12
ANXA1 annexin A1
CD8A CD8a molecule
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CRIP1 cysteine-rich protein 1 (intestinal)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KRT7 keratin 7, type II
LUC7L3 LUC7-like 3 (S. cerevisiae)
PEG3 paternally expressed 3
PWP1 PWP1 homolog (S. cerevisiae)
TPD52L1 tumor protein D52-like 1
TSPAN6 tetraspanin 6