BRD-K18059238_GAMMA-LINOLENIC ACID (18:3 n-6)_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K18059238_GAMMA-LINOLENIC ACID (18:3 n-6)_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
BEX1 brain expressed, X-linked 1
BPTF bromodomain PHD finger transcription factor
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CRELD2 cysteine-rich with EGF-like domains 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
EMP1 epithelial membrane protein 1
FAM198B family with sequence similarity 198, member B
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FGL2 fibrinogen-like 2
FN1 fibronectin 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHEX hematopoietically expressed homeobox
HIST1H1C histone cluster 1, H1c
IL13RA1 interleukin 13 receptor, alpha 1
KCTD12 potassium channel tetramerization domain containing 12
KIAA1033 KIAA1033
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MMP7 matrix metallopeptidase 7
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAWR PRKC, apoptosis, WT1, regulator
PEG10 paternally expressed 10
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PPAP2B phosphatidic acid phosphatase type 2B
PRPF4B pre-mRNA processing factor 4B
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPRED2 sprouty-related, EVH1 domain containing 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLR4 toll-like receptor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
UGDH UDP-glucose 6-dehydrogenase
WLS wntless Wnt ligand secretion mediator
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AGR2 anterior gradient 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BST2 bone marrow stromal cell antigen 2
CHL1 cell adhesion molecule L1-like
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EFNB2 ephrin-B2
EIF5A eukaryotic translation initiation factor 5A
FKBP9 FK506 binding protein 9, 63 kDa
GOLM1 golgi membrane protein 1
GSTP1 glutathione S-transferase pi 1
HOXC6 homeobox C6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LAMC2 laminin, gamma 2
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP1B microtubule-associated protein 1B
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPY neuropeptide Y
POPDC3 popeye domain containing 3
PTMA prothymosin, alpha
RPL36 ribosomal protein L36
RPL37A ribosomal protein L37a
RPS26 ribosomal protein S26
TM9SF3 transmembrane 9 superfamily member 3
TPD52L1 tumor protein D52-like 1
TUBB6 tubulin, beta 6 class V
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WBSCR22 Williams Beuren syndrome chromosome region 22
WDTC1 WD and tetratricopeptide repeats 1
ZBTB18 zinc finger and BTB domain containing 18