BRD-K17739445_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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71 genes differentially expressed following the BRD-K17739445_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDOB aldolase B, fructose-bisphosphate
ANXA10 annexin A10
AREG amphiregulin
ATF3 activating transcription factor 3
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CCL20 chemokine (C-C motif) ligand 20
CD52 CD52 molecule
CLTC clathrin, heavy chain (Hc)
EREG epiregulin
FOXF1 forkhead box F1
FSD1 fibronectin type III and SPRY domain containing 1
GCLC glutamate-cysteine ligase, catalytic subunit
HIST1H1C histone cluster 1, H1c
IVNS1ABP influenza virus NS1A binding protein
KLF6 Kruppel-like factor 6
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MT1E metallothionein 1E
NSG1 neuron specific gene family member 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERINC5 serine incorporator 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SOX11 SRY (sex determining region Y)-box 11
TBX2 T-box 2
TF transferrin
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ANKRD10 ankyrin repeat domain 10
CALD1 caldesmon 1
CCL5 chemokine (C-C motif) ligand 5
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
CST1 cystatin SN
DLG5 discs, large homolog 5 (Drosophila)
DMD dystrophin
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GOLGA8A golgin A8 family, member A
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
MERTK MER proto-oncogene, tyrosine kinase
METRN meteorin, glial cell differentiation regulator
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NKG7 natural killer cell granule protein 7
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDE4D phosphodiesterase 4D, cAMP-specific
PNISR PNN-interacting serine/arginine-rich protein
RPS11 ribosomal protein S11
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
STOM stomatin
SVIL supervillin
TARP TCR gamma alternate reading frame protein
TESC tescalcin
TSPYL5 TSPY-like 5
USP48 ubiquitin specific peptidase 48