BRD-K16977723_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the BRD-K16977723_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD52 CD52 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
DYNLT1 dynein, light chain, Tctex-type 1
EPCAM epithelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
MAN1A1 mannosidase, alpha, class 1A, member 1
MEST mesoderm specific transcript
ORC1 origin recognition complex, subunit 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
SHB Src homology 2 domain containing adaptor protein B

decreased expression

Symbol Name
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
ELOVL5 ELOVL fatty acid elongase 5
GSN gelsolin
LAMP5 lysosomal-associated membrane protein family, member 5
MGP matrix Gla protein
RUNX1 runt-related transcription factor 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SPARCL1 SPARC-like 1 (hevin)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
UGCG UDP-glucose ceramide glucosyltransferase