BRD-K16940042_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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28 genes differentially expressed following the BRD-K16940042_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
BLNK B-cell linker
COL11A1 collagen, type XI, alpha 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
GCLC glutamate-cysteine ligase, catalytic subunit
HIST1H2BC histone cluster 1, H2bc
LAMP1 lysosomal-associated membrane protein 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
SH3BGRL SH3 domain binding glutamate-rich protein like
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1

decreased expression

Symbol Name
AIM1 absent in melanoma 1
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
CBR3 carbonyl reductase 3
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL14 chemokine (C-X-C motif) ligand 14
EXOSC4 exosome component 4
GPER1 G protein-coupled estrogen receptor 1
JADE2 jade family PHD finger 2
PDZD2 PDZ domain containing 2
PPAP2B phosphatidic acid phosphatase type 2B
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPDEF SAM pointed domain containing ETS transcription factor
TLK2 tousled-like kinase 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6