BRD-K16940042_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K16940042_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACADVL acyl-CoA dehydrogenase, very long chain
BAMBI BMP and activin membrane-bound inhibitor
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CPA3 carboxypeptidase A3 (mast cell)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DPT dermatopontin
DUSP1 dual specificity phosphatase 1
ETV5 ets variant 5
GJA1 gap junction protein, alpha 1, 43kDa
GPM6B glycoprotein M6B
LCN2 lipocalin 2
MAP1B microtubule-associated protein 1B
MATN2 matrilin 2
OLFM4 olfactomedin 4
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
SCGB2A1 secretoglobin, family 2A, member 1
SFN stratifin
TMEM45A transmembrane protein 45A
TOR1A torsin family 1, member A (torsin A)
TOX3 TOX high mobility group box family member 3
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
BACE2 beta-site APP-cleaving enzyme 2
CXCL12 chemokine (C-X-C motif) ligand 12
FABP7 fatty acid binding protein 7, brain
FXYD5 FXYD domain containing ion transport regulator 5
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
KDM5D lysine (K)-specific demethylase 5D
MAGEA3 melanoma antigen family A3
MCTP2 multiple C2 domains, transmembrane 2
PPARG peroxisome proliferator-activated receptor gamma
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TSPAN4 tetraspanin 4