BRD-K16940042_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K16940042_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
APOA2 apolipoprotein A-II
BIK BCL2-interacting killer (apoptosis-inducing)
CD24 CD24 molecule
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL6A3 collagen, type VI, alpha 3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FGB fibrinogen beta chain
HIST1H1C histone cluster 1, H1c
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
LCN2 lipocalin 2
PEG3 paternally expressed 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
CA2 carbonic anhydrase II
CLEC2B C-type lectin domain family 2, member B
HBB hemoglobin, beta
HBD hemoglobin, delta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IGFBP3 insulin-like growth factor binding protein 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
NEFH neurofilament, heavy polypeptide
NME4 NME/NM23 nucleoside diphosphate kinase 4
PLIN2 perilipin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TXNDC9 thioredoxin domain containing 9